Understanding Cooperativity in Homo- and Heterometallic Complexes: From Basic Concepts to Design

Cooperative effects have attracted considerable attention in recent years. These effects are ubiquitous in chemistry and biology and can govern interactions of proteins with other biomolecules, mechanisms of supramolecular recognition and polymerization, catalysis, assembly of compounds on surfaces, and physical properties such as magnetic, electronic or optical properties, e. g. Consequently, the understanding of cooperative effects can lead to a structure-property relation that can pave the way to future applications in various research areas; however, with regard to cooperative effects in homo- and heterometallic complexes, we still are at the beginning of understanding. Nevertheless, concepts to describe cooperativity of metal centers as well as methodologies to investigate and model these effects have emerged over the last years. This concept article gives an overview of these existing concepts, approaches, and strategies to understand cooperative effects in homo- and heterometallic complexes. Special emphasis is put on concepts to define cooperative effects, their quantification, as well as methods to investigate cooperative effects. Cooperative effects can govern the reactivity, chemical as well as physical properties of homo- and heterometallic complexes. In the last approximately 15 years, the understanding of cooperative effects has increased drastically. This concept article briefly summarizes basic concepts used to describe, quantify and investigate cooperative effects. image