Anti-Inflammatory Effects of Peripheral Dopamine

被引：18
作者：
Moore, Shaun C. [1 ]
de Castro, Pedro A. S. Vaz [1 ]
Yaqub, Daniel [1 ]
Jose, Pedro A. [1 ]
Armando, Ines [1 ]
机构：
[1] George Washington Univ, Sch Med & Hlth Sci, Div Kidney Dis & Hypertens, Dept Med, Washington, DC 20037 USA
来源：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2023年 / 24卷 / 18期
关键词：
immune cells; signaling pathways; kidney; mesenteric organs; pro-inflammatory factors; D2 RECEPTOR GENE; OXYGEN SPECIES PRODUCTION; LOWERS BLOOD-PRESSURE; ACUTE KIDNEY INJURY; ACUTE LIVER-INJURY; FACTOR-KAPPA-B; OXIDATIVE STRESS; C957T POLYMORPHISM; D-2; RECEPTOR; LIPOPOLYSACCHARIDE/D-GALACTOSAMINE;
D O I：
10.3390/ijms241813816
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Dopamine is synthesized in the nervous system where it acts as a neurotransmitter. Dopamine is also synthesized in a number of peripheral organs as well as in several types of cells and has organ-specific functions and, as demonstrated more recently, is involved in the regulation of the immune response and inflammatory reaction. In particular, the renal dopaminergic system is very important in the regulation of sodium transport and blood pressure and is particularly sensitive to stimuli that cause oxidative stress and inflammation. This review is focused on how dopamine is synthesized in organs and tissues and the mechanisms by which dopamine and its receptors exert their effects on the inflammatory response.
引用
收藏
页数：21
相关论文
共 224 条
[61]   SOURCE AND PHYSIOLOGICAL SIGNIFICANCE OF PLASMA 3,4-DIHYDROXYPHENYLALANINE IN THE RAT [J].
EISENHOFER, G ;
GOLDSTEIN, DS ;
ROPCHAK, TG ;
KOPIN, IJ .
JOURNAL OF NEUROCHEMISTRY, 1988, 51 (04) :1204-1213
[62]   INCREASE IN PLASMA 3,4-DIHYDROXYPHENYLALANINE (DOPA) APPEARANCE RATE AFTER INHIBITION OF DOPA DECARBOXYLASE IN HUMANS [J].
ELDRUP, E ;
HETLAND, ML ;
CHRISTENSEN, NJ .
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1994, 24 (03) :205-211
[63]   Association of Peripheral Inflammatory Biomarkers and Growth Factors Levels with Sex, Therapy and Other Clinical Factors in Schizophrenia and Patient Stratification Based on These Data [J].
Ermakov, Evgeny A. ;
Melamud, Mark M. ;
Boiko, Anastasiia S. ;
Kamaeva, Daria A. ;
Ivanova, Svetlana A. ;
Nevinsky, Georgy A. ;
Buneva, Valentina N. .
BRAIN SCIENCES, 2023, 13 (05)
[64]   An affected pedigree member analysis of linkage between the dopamine D2 receptor gene TaqI polymorphism and obesity and hypertension [J].
Fang, YJ ;
Thomas, GN ;
Xu, ZL ;
Fang, JQ ;
Critchley, AJH ;
Tomlinson, B .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2005, 102 (01) :111-116
[65]   New roles for dopamine D2and D3receptors in pancreatic beta cell insulin secretion [J].
Farino, Zachary J. ;
Morgenstern, Travis J. ;
Maffei, Antonella ;
Quick, Matthias ;
De Solis, Alain J. ;
Wiriyasermkul, Pattama ;
Freyberg, Robin J. ;
Aslanoglou, Despoina ;
Sorisio, Denise ;
Inbar, Benjamin P. ;
Free, R. Benjamin ;
Donthamsetti, Prashant ;
Mosharov, Eugene, V ;
Kellendonk, Christoph ;
Schwartz, Gary J. ;
Sibley, David R. ;
Schmauss, Claudia ;
Zeltser, Lori M. ;
Moore, Holly ;
Harris, Paul E. ;
Javitch, Jonathan A. ;
Freyberg, Zachary .
MOLECULAR PSYCHIATRY, 2020, 25 (09) :2070-2085
[66]   Nrf2 inhibition induces oxidative stress, renal inflammation and hypertension in mice [J].
Farooqui, Zeba ;
Mohammad, Razia Sultana ;
Lokhandwala, Mustafa F. ;
Banday, Anees Ahmad .
CLINICAL AND EXPERIMENTAL HYPERTENSION, 2021, 43 (02) :175-180
[67]   Dopaminergic Control of Inflammation and Glycemia in Sepsis and Diabetes [J].
Feketeova, Eleonora ;
Li, Zhifeng ;
Joseph, Biju ;
Shah, Roshan ;
Spolarics, Zoltan ;
Ulloa, Luis .
FRONTIERS IN IMMUNOLOGY, 2018, 9
[68]   Immunomodulatory Effects of Dopamine in Inflammatory Diseases [J].
Feng, Yifei ;
Lu, Yan .
FRONTIERS IN IMMUNOLOGY, 2021, 12
[69]   Involvement of dopamine D2 receptors activation in ischemic post-conditioning-induced cardioprotection through promoting PKC-ε particulate translocation in isolated rat hearts [J].
Gao, Jun ;
Guo, Jin ;
Li, Hongxia ;
Bai, Shuzhi ;
Li, Hong ;
Wu, Bo ;
Wang, Lina ;
Xi, Yuhui ;
Tian, Ye ;
Yang, Guangdong ;
Wang, Rui ;
Wu, Lingyun ;
Xu, Changqing ;
Li, Hongzhu .
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2013, 379 (1-2) :267-276
[70]   Integrating Human and Rodent Data to Identify the Genetic Factors Involved in Chronic Kidney Disease [J].
Garrett, Michael R. ;
Pezzolesi, Marcus G. ;
Korstanje, Ron .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2010, 21 (03) :398-405
234567891011