[18F]F-Choline PET/CT and 4D-CT in the evaluation of primary hyperparathyroidism: rivals or allies?

被引:10
作者
Fiz, Francesco [1 ]
Bottoni, Gianluca [1 ]
Massollo, Michela [1 ]
Trimboli, Pierpaolo [2 ,3 ]
Catrambone, Ugo [4 ]
Bacigalupo, Lorenzo [5 ]
Righi, Sergio [6 ]
Treglia, Giorgio [3 ,7 ,8 ]
Imperiale, Alessio [1 ,9 ,10 ]
Piccardo, Arnoldo [1 ]
机构
[1] Osped Galliera, Dept Nucl Med, Genoa, Italy
[2] Ente Osped Cantonale, Clin Endocrinol & Diabetol, Bellinzona, Switzerland
[3] Univ Svizzera Italiana USI, Fac Biomed Sci, Lugano, Switzerland
[4] Osped Galliera, Dept Gen & Endocrine Surg, Genoa, Italy
[5] Osped Galliera, Dept Radiol, Genoa, Italy
[6] Osped Galliera, Dept Med Phys, Genoa, Italy
[7] Ente Osped Cantonale, Imaging Inst Southern Switzerland, Clin Nucl Med, Bellinzona, Switzerland
[8] Univ Lausanne, Lausanne Univ Hosp, Dept Nucl Med & Mol Imaging, Lausanne, Switzerland
[9] Strasbourg Univ Hosp, Inst Cancerol Strasbourg Europe ICANS, Dept Nucl Med & Mol Imaging, Strasbourg, France
[10] unistra, IPHC, Dept Radiobiol Hadrontherapy & Mol Imaging DRHIM, UMR 7178,CNRS, Strasbourg, France
关键词
Positron emission tomography computed tomography; Four-Dimensional Computed Tomography; Fluoromethylcholine; Hyper-parathyroidism; primary; Diagnostic imaging; SURGERY; LOCALIZATION; SCINTIGRAPHY; ULTRASOUND; CT;
D O I
10.23736/S1824-4785.23.03514-8
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Primary hyperparathyroidism is a hard-to-diagnose condition that can run without symptoms for many years without causing symptoms; yet, it can cause dire long-term consequences, such as osteoporosis and renal impairment. First-line diagnostic methods include ultrasound and para-thyroid scintigraphy, which provide unsatisfactory results in terms of detection rate. Second-line imaging methods include [18F]F-Choline PET/ CT, 4D-CT, and their combination. These methods have shown a great detection rate and sensitivity; however, they are to this day less wide-spread than the first-line ones. Both the two methods (PET and 4D-CT) have their specific advantages and field of application, as well as their specific limitations. In this narrative review, we will describe the advantages and disadvantages of the two techniques extensively. Moreover, we will try to identify whether the combined examination can play a role and how relevant this role is. Finally, we will try to define the specific clinical situation in which each method can provide the best contribution to diagnosing parathyroid tissue hyperfunction.
引用
收藏
页码:130 / 137
页数:8
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