Thyroid [123I]MIBG uptake in Parkinson?s disease and diabetes mellitus

被引：1
作者：
Fedorova, Tatyana D. [1 ,2 ,3 ,7 ,8 ]
Knudsen, Karoline [1 ,2 ,3 ]
Rasmussen, Thorsten K. [3 ,4 ,5 ]
Horsager, Jacob [1 ,2 ]
Nahimi, Adjmal [1 ,2 ]
Skjaerbaek, Casper [1 ,2 ,4 ,5 ]
Schaeffer, Eva [6 ]
Berg, Daniela [6 ]
Terkelsen, Astrid J. [4 ,5 ]
Borghammer, Per [1 ,2 ,3 ]
机构：
[1] Aarhus Univ Hosp, Dept Nucl Med, Aarhus, Denmark
[2] Aarhus Univ Hosp, PET Ctr, Aarhus, Denmark
[3] Aarhus Univ, Dept Clin Med, Aarhus, Denmark
[4] Aarhus Univ Hosp, Dept Neurol, Aarhus, Denmark
[5] Aarhus Univ Hosp, Danish Pain Res Ctr, Aarhus, Denmark
[6] Christian Albrechts Univ Kiel, Dept Neurol, Kiel, Germany
[7] Dept Nucl Med, Palle Juul Jensens Blvd 165, DK-8200 Aarhus N, Denmark
[8] PET Ctr, Palle Juul Jensens Blvd 165, DK-8200 Aarhus N, Denmark
来源：
IBRO NEUROSCIENCE REPORTS | 2023年 / 14卷
关键词：
Parkinson?s disease; Diabetes mellitus; MIBG; Thyroid gland; Scintigraphy; SYMPATHETIC DENERVATION; ORTHOSTATIC HYPOTENSION; MIBG UPTAKE; SCINTIGRAPHY;
D O I：
10.1016/j.ibneur.2023.03.006
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Thyroid [123I]MIBG uptake is proposed as a tool for differentiating between Parkinson's disease (PD) and dia-betes mellitus (DM) on [123I]MIBG scintigraphies since both patient groups show decreased cardiac uptake. One study compared thyroid [123I]MIBG uptake in DM and PD patients and reported reduced [123I]MIBG uptake only in the PD group. Here, we investigated thyroid [123I]MIBG uptake in patients with PD and DM and found severely reduced thyroid [123I]MIBG uptake in DM. Larger studies are needed to substantiate whether DM patients are more or less likely to exhibit decreased thyroid MIBG uptake compared to controls and PD patients.
引用
收藏
页码：342 / 345
页数：4
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