Role of ClpP in the anti-cancer effects of imipridone ONC201 and ONC206

被引:0
|
作者
Lee, Andrew
Maranto, Cristina
Foster, Scott
Morrow, Sara
Allen, Joshua E.
Lanier, Randall
Sethna, Phiroze
Prabhu, Varun V.
机构
关键词
D O I
10.1158/1538-7445.AM2023-4914
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4914
引用
收藏
页数:2
相关论文
共 50 条
  • [1] ROLE OF CLPP AND MITOCHONDRIAL METABOLISM IN THE ANTI-CANCER EFFECTS OF IMIPRIDONE ONC201 AND ONC206 IN GLIOBLASTOMA AND DIPG
    Foster, Scott
    Lee, Andrew
    Maranto, Cristina
    Allen, Joshua E.
    Lanier, Randall
    Sethna, Phiroze
    Prabhu, Varun V.
    NEURO-ONCOLOGY, 2022, 24 : 234 - 234
  • [2] Adaptation to dopamine impairs the anti-cancer effect of ONC201 and ONC206
    Zhang, Yiqun
    El-Deiry, Wafik S.
    CANCER RESEARCH, 2022, 82 (12)
  • [3] MOLECULAR DIFFERENTIATION OF IMIPRIDONES ONC201 AND ONC206
    Prabhu, Varun
    Cuoco, Caroline
    Jung, Jinkyu
    Morrow, Sara
    Kawakibi, Abed Rahman
    Willette, Blair
    Day, Marilyn
    Anantharaman, Lakshmi
    Charter, Neil
    Rucker, Joseph
    Doranz, Benjamin
    Basken, Joel
    Stogniew, Martin
    Gilbert, Mark
    Free, R.
    Sibley, David
    Allen, Joshua
    NEURO-ONCOLOGY, 2020, 22 : 68 - 68
  • [4] ClpP drives efficacy and mediates acquired resistance with imipridones ONC201 and ONC206 in glioma in vitro
    Maranto, Cristina
    Foster, Scott
    Lee, Andrew
    Sethna, Phiroze
    Allen, Joshua E.
    Prabhu, Varun V.
    CANCER RESEARCH, 2024, 84 (05)
  • [5] Predictive biomarker evaluation for the anti-cancer imipridone ONC201
    Morrow, Sara
    Prabhu, Varun Vijay
    Allen, Joshua E.
    Oster, Wolfgang
    CANCER RESEARCH, 2020, 80 (16)
  • [6] ONC201 and ONC206: Metabolically ClipPing the wings of diffuse midline glioma
    Purow, Benjamin
    NEURO-ONCOLOGY, 2022, 24 (09) : 1452 - 1453
  • [7] CYP450 AND METABOLIC PROFILING OF ANTI-CANCER IMIPRIDONE ONC201
    Morrow, Sara
    Prabhu, Varun
    Tarapore, Rohinton S.
    Guo, Ailan
    Fang, Yunlan
    Nej, Magdalena
    Stogniew, Martin
    Allen, Joshua
    NEURO-ONCOLOGY, 2020, 22 : 102 - 102
  • [8] Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212
    Wagner, Jessica
    Kline, Christina Leah
    Ralff, Marie D.
    Lev, Avital
    Lulla, Amriti
    Zhou, Lanlan
    Olson, Gary L.
    Nallaganchu, Bhaskara Rao
    Benes, Cyril H.
    Allen, Joshua E.
    Prabhu, Varun V.
    Stogniew, Martin
    Oster, Wolfgang
    El-Deiry, Wafik S.
    CELL CYCLE, 2017, 16 (19) : 1790 - 1799
  • [9] Differential activation of the integrated stress response correlates with anti -tumor activity of imipridones ONC201 and ONC206 in pediatric sarcomas
    Allegakoen, David V.
    Tarapore, Rohinton S.
    Allen, Joshua E.
    Sabnis, Amit J.
    Bivona, Trever G.
    CANCER RESEARCH, 2019, 79 (13)
  • [10] Receptor pharmacology and anti-cancer activity of selective DRD2/3 antagonist imipridone ONC206
    Prabhu, Varun Vijay
    Madhukar, Neel
    Tarapore, Rohinton
    Garnett, Mathew
    McDermott, Ultan
    Benes, Cyril
    Charter, Neil
    Deacon, Sean
    VanEngelenburg, Alexander
    Rucker, Joseph
    Doranz, Benjamin
    Elemento, Olivier
    Oster, Wolfgang
    Stogniew, Martin
    Allen, Joshua
    CANCER RESEARCH, 2018, 78 (13)