Exosomes as a potential therapeutic approach in osteoimmunology

被引：3
|
作者：
Zhivodernikov, Ivan V. [1 ]
Markina, Yuliya V. [1 ]
Kirichenko, Tatiana V. [1 ]
Popov, Mikhail A. [2 ]
Markin, Alexander M. [1 ,3 ]
机构：
[1] Petrovsky Natl Res Ctr Surg, Lab Cellular & Mol Pathol Cardiovasc Syst, Moscow, Russia
[2] Moscow Reg Res & Clin Inst MONIKI, Dept Cardiac Surg, Moscow, Russia
[3] Peoples Friendship Univ Russia, Med Inst, Moscow 117198, Russia
来源：
FRONTIERS IN IMMUNOLOGY | 2023年 / 14卷
基金：
俄罗斯科学基金会;
关键词：
exosomes; osteoimmunology; target therapy; immune system; osteoporosis; MESENCHYMAL STEM-CELLS; EXTRACELLULAR VESICLES; OSTEOBLASTS; MECHANISMS; REVERSAL; EFFICACY; TARGET;
D O I：
10.3389/fimmu.2023.1309015
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Exosomes are natural extracellular vesicles that play a key role in inter- and intracellular communication. Currently they are considered as a promising therapeutic strategy for the treatment of various diseases. In osteoimmunology, exosomes can serve as biomarkers of bone homeostasis disorders and, at the same time, promising therapeutic agents with high stability in the biological environment, low immunogenicity and good bioavailability. In this review, we attempted to examine exosomes as natural mediators of intercellular communication, playing an essential role in the interaction of the immune system and bone tissue, based on an analysis of the PubMed database up to October 2023.
引用
收藏
页数：8
相关论文
共 50 条
  • [1] Therapeutic Potential of Exosomes in Pulmonary Fibrosis
    Xie, Linshen
    Zeng, Ye
    FRONTIERS IN PHARMACOLOGY, 2020, 11
  • [2] Potential Therapeutic Effects of Exosomes in Regenerative Endodontics
    Yu, Sijing
    Chen, Hao
    Gao, Bo
    ARCHIVES OF ORAL BIOLOGY, 2020, 120
  • [3] The potential of exosomes as a new therapeutic strategy for glioblastoma
    Silva, Leonor Cunha
    Branco, Francisco
    Cunha, Joana
    Vitorino, Carla
    Gomes, Celia
    Carrascal, Mylene A.
    Falcao, Amilcar
    Neves, Bruno Miguel
    Cruz, Maria Teresa
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2024, 203
  • [4] The Therapeutic Potential of Exosomes in Soft Tissue Repair and Regeneration
    Wan, Rou
    Hussain, Arif
    Behfar, Atta
    Moran, Steven L.
    Zhao, Chunfeng
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (07)
  • [5] Therapeutic potential of exosomes in spermatogenesis regulation and male infertility
    Mohammadi, Amirhossein
    Shabani, Ronak
    Bashiri, Zahra
    Rafiei, Sara
    Asgari, Hamidreza
    Koruji, Morteza
    BIOLOGY OF THE CELL, 2024, 116 (06)
  • [6] The potential application of encapsulated exosomes: A new approach to increase exosomes therapeutic efficacy
    Hazrati, Ali
    Mirsanei, Zahra
    Heidari, Neda
    Malekpour, Kosar
    Rahmani-Kukia, Nasim
    Abbasi, Ardeshir
    Soudi, Sara
    BIOMEDICINE & PHARMACOTHERAPY, 2023, 162
  • [7] The therapeutic potential of exosomes in lung cancer
    Liang, Hongyuan
    Zhang, Lingyun
    Zhao, Xiangxuan
    Rong, Jian
    CELLULAR ONCOLOGY, 2023, 46 (05) : 1181 - 1212
  • [8] Exosomes: roles and therapeutic potential in osteoarthritis
    Ni, Zhenhong
    Zhou, Siru
    Li, Song
    Kuang, Liang
    Chen, Hangang
    Luo, Xiaoqing
    Ouyang, Junjie
    He, Mei
    Du, Xiaolan
    Chen, Lin
    BONE RESEARCH, 2020, 8 (01)
  • [9] Exosomes: Natural Nanoparticles with Therapeutic Potential
    Ratushnyak, M. G.
    Semochkina, Yu. P.
    NANOTECHNOLOGIES IN RUSSIA, 2020, 15 (7-8): : 415 - 427
  • [10] The role and therapeutic potential of MSC-derived exosomes in osteoarthritis
    Bao, Chuncha
    He, Chengqi
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021, 710
12345