Metastatic Renal Cell Carcinoma and Unforeseen Adrenal Insufficiency: A Case Report and Literature Review

被引:0
作者
Repp, Matthew L. [1 ]
Alvarez, Rodrigo A. [2 ]
Arevalo-Salazar, Dory E. [3 ]
Kotagiri, Rajesh [2 ]
机构
[1] Univ Arizona, Coll Med, Med Sch, Tucson, AZ 85721 USA
[2] Univ Arizona, Coll Med, Internal Med, Tucson, AZ USA
[3] Univ Arizona, Coll Med, Pathol, Tucson, AZ USA
关键词
adrenal gland injury; metastatic kidney cancer; adrenal insufficiency; renal cell carcinoma; genitourinary oncology; SITES;
D O I
10.7759/cureus.35265
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Renal cell carcinoma (RCC) can metastasize to nearly every organ, yet rarely metastasizes to the adrenal glands despite their anatomical proximity. Adrenal metastases are typically incidental findings on medical imaging and are vastly clinically asymptomatic. The adrenal glands can maintain hormonal homeostasis if a tenth of total adrenal gland function is preserved. We present a patient with synchronous bilateral adrenal metastases from RCC with rapid and unexpected development of adrenal insufficiency (AI).
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相关论文
共 27 条
[1]   Distribution of metastatic sites in renal cell carcinoma: a population-based analysis [J].
Bianchi, M. ;
Sun, M. ;
Jeldres, C. ;
Shariat, S. F. ;
Trinh, Q. -D. ;
Briganti, A. ;
Tian, Z. ;
Schmitges, J. ;
Graefen, M. ;
Perrotte, P. ;
Menon, M. ;
Montorsi, F. ;
Karakiewicz, P. I. .
ANNALS OF ONCOLOGY, 2012, 23 (04) :973-980
[2]   Metastatic renal cell carcinoma without evidence of a renal primary [J].
Costantino, Corey ;
Thomas, George V. ;
Ryan, Christopher ;
Coakley, Fergus V. ;
Troxell, Megan L. .
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2016, 48 (01) :73-77
[3]  
Dudani S, 2020, J CLIN ONCOL, V38
[4]   RENAL-CELL CARCINOMA CAUSING A SELECTIVE MINERALOCORTICOID INSUFFICIENCY [J].
GOFFMAN, TE ;
SCHECHTER, GP ;
MCKEEN, EA ;
MARIANICOSTANTINI, R ;
SCHEIN, PS .
JOURNAL OF UROLOGY, 1982, 128 (02) :370-371
[5]   Vaginal Bleeding as Initial Presentation of an Aggressive Renal Cell Carcinoma: A Case Report and Review of the Literature [J].
Jimenez, Antonio R. ;
Rolon, Maria del Mar Rivera ;
Eyzaguirre, Eduardo ;
Clement, Cecilia .
CASE REPORTS IN PATHOLOGY, 2018, 2018
[6]  
Koutalellis Georgios E, 2009, Cases J, V2, P7298, DOI 10.4076/1757-1626-2-7298
[7]  
Kravvas Georgios, 2014, Case Rep Urol, V2014, P840163, DOI 10.1155/2014/840163
[8]   Bilateral adrenal metastasis of renal cell carcinoma 4 years after radical nephrectomy A case report and review of literature [J].
Li, Yingjie ;
Ji, Zhigang ;
Wang, Dong ;
Xie, Yi .
MEDICINE, 2021, 100 (31) :E26838
[9]   ASPIRATION CYTOLOGY OF SIMULTANEOUS BILATERAL ADRENAL METASTASES FROM RENAL-CELL CARCINOMA - A CASE-REPORT AND REVIEW OF THE LITERATURE [J].
LUCIANI, L ;
SCAPPINI, P ;
PUSIOL, T ;
PISCIOLI, F .
JOURNAL OF UROLOGY, 1985, 134 (02) :315-318
[10]   Adrenocortical function in patients with macrometastases of the adrenal gland [J].
Lutz, A ;
Stojkovic, M ;
Schmidt, M ;
Arlt, W ;
Allolio, B ;
Reincke, M .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2000, 143 (01) :91-97