Pro-and Antioxidant Status in Newborn with COVID-19

被引：3

作者：

Rychkova, L. V. ^{[1
]}

Darenskaya, M. A. ^{[1
]}

Petrova, A. G. ^{[1
]}

Semenova, N. V. ^{[1
]}

Moskaleva, E. V. ^{[1
]}

Kolesnikov, S. I. ^{[1
]}

Vanyarkina, A. S. ^{[1
]}

Kolesnikova, L. I. ^{[1
]}

机构：

[1] Sci Ctr Family Hlth & Human Reprod Problems, Irkutsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2023年 / 174卷 / 04期

关键词：

COVID-19; oxidative stress; antioxidants; newborns; children; OXIDATIVE STRESS;

D O I：

10.1007/s10517-023-05730-4

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

There is practically no information on the state of oxidative stress reactions in newborns with coronavirus infections. At the same time, such studies are extremely important and can contribute to better understanding of the process of reactivity in patients of different ages. The content of pro- and antioxidant status indicators was assessed in 44 newborns with confirmed COVID-19. It was found that the content of compounds with unsaturated double bonds, primary, secondary, and final LPO products were elevated in newborns with COVID-19. These changes were accompanied by higher SOD activity and retinol level and reduced activity of glutathione peroxidase. Contrary to popular opinion, newborns can be a COVID-19-susceptible age group and require more close monitoring of metabolic reactions during the period of neonatal adaptation that is an aggravating background during infection.

引用

页码：464 / 467

页数：4

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