Effectiveness of Fecal Microbiota Transplantation Treatment in Patients with Recurrent Clostridium Difficile Infection, Ulcerative Colitis, and Crohn's Disease: A Systematic Review

被引:5
作者
Jaramillo, Arturo P. [1 ]
Awosusi, Babatope L. [2 ]
Ayyub, Javaria [3 ]
Dabhi, Karan Nareshbhai [3 ]
V. Gohil, Namra [3 ,4 ]
Tanveer, Nida
Hussein, Sally [3 ]
Pingili, Shravya [5 ,6 ]
Makkena, Vijaya Krishna [3 ,7 ]
机构
[1] Calif Inst Behav Neurosci & Psychol, Gen Practice, Fairfield, CA 94534 USA
[2] Calif Inst Behav Neurosci & Psychol, Pathol & Lab Med, Fairfield, CA USA
[3] Calif Inst Behav Neurosci & Psychol, Internal Med, Fairfield, CA USA
[4] Baroda Med Coll, Internal Med, Vadodara, India
[5] Faisalabad Med Univ, Allied Hosp, Internal Med, Faisalabad, Pakistan
[6] Kakatiya Med Coll, Internal Med, Hyderabad, Pakistan
[7] Osmania Med Coll & Hosp, Internal Med, Hyderabad, Pakistan
关键词
irritable bowel disease; chron's disease; ulcerative colitis (uc); fecal microbiota transplantation clostridium difficile infection; clostridium difficile infection treatment; REMISSION;
D O I
10.7759/cureus.42120
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cronh's disease and ulcerative colitis (UC) are diseases with unknown etiologies that cause ongoing inflammation in the gastrointestinal system. Chron's disease causes immunological dysregulation, and UC causes intestinal harm due to immune reactions. According to our study, fecal microbiota transplantation (FMT) has many benefits in the treatment of inflammatory bowel disease (IBD) by restoring intestinal homeostasis and reducing clinical symptoms. In mildly symptomatic patients with UC, an FMT treatment combined with an anti-inflammatory diet can produce remission, which would then be followed by a diet that maintained the anti-inflammatory effects. The efficacy of FMT consists of preventing flares or the consequences of IBD. As a result, we must emphasize that more investigation should be done before developing a therapeutic procedure for FMT in IBD and its associated consequences.
引用
收藏
页数:6
相关论文
共 21 条
[1]   Both Fidaxomicin and Vancomycin Inhibit Outgrowth of Clostridium difficile Spores [J].
Allen, Charlotte A. ;
Babakhani, Farah ;
Sears, Pam ;
Ly Nguyen ;
Sorg, Joseph A. .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 57 (01) :664-667
[2]  
[Anonymous], 2022, WHAT IS KNOWN FECAL
[3]   Fecal Microbiota Transplantation in Inflammatory Bowel Disease [J].
Boicean, Adrian ;
Birlutiu, Victoria ;
Ichim, Cristian ;
Anderco, Paula ;
Birsan, Sabrina .
BIOMEDICINES, 2023, 11 (04)
[4]   Fecal microbiota transplantation for the treatment of recurrent and severe Clostridium difficile infection in solid organ transplant recipients: A multicenter experience [J].
Cheng, Yao-Wen ;
Phelps, Emmalee ;
Ganapini, Vincent ;
Khan, Noor ;
Ouyang, Fangqian ;
Xu, Huiping ;
Khanna, Sahil ;
Tariq, Raseen ;
Friedman-Moraco, Rachel J. ;
Woodworth, Michael H. ;
Dhere, Tanvi ;
Kraft, Colleen S. ;
Kao, Dina ;
Smith, Justin ;
Le, Lien ;
El-Nachef, Najwa ;
Kaur, Nirmal ;
Kowsika, Sree ;
Ehrlich, Adam ;
Smith, Michael ;
Safdar, Nasia ;
Misch, Elizabeth Ann ;
Allegretti, Jessica R. ;
Flynn, Ann ;
Kassam, Zain ;
Sharfuddin, Asif ;
Vuppalanchi, Raj ;
Fischer, Monika .
AMERICAN JOURNAL OF TRANSPLANTATION, 2019, 19 (02) :501-511
[5]   Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis A Randomized Clinical Trial [J].
Costello, Samuel P. ;
Hughes, Patrick A. ;
Waters, Oliver ;
Bryant, Robert, V ;
Vincent, Andrew D. ;
Blatchford, Paul ;
Katsikeros, Rosa ;
Makanyanga, Jesica ;
Campaniello, Melissa A. ;
Mavrangelos, Chris ;
Rosewarne, Carly P. ;
Bickley, Chelsea ;
Peters, Cian ;
Schoeman, Mark N. ;
Conlon, Michael A. ;
Roberts-Thomson, Ian C. ;
Andrews, Jane M. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2019, 321 (02) :156-164
[6]   Early Results of Fecal Microbial Transplantation Protocol Implementation at a Community-based University Hospital [J].
Duarte-Chavez, Rodrigo ;
Wojda, Thomas R. ;
Zanders, Thomas B. ;
Geme, Berhanu ;
Fioravanti, Gloria ;
Stawicki, Stanislaw P. .
JOURNAL OF GLOBAL INFECTIOUS DISEASES, 2018, 10 (02) :47-57
[7]   Fecal Microbiota Therapy for Recurrent Clostridium difficile Infection in HIV-Infected Persons [J].
Elopre, Latesha ;
Rodriguez, Martin .
ANNALS OF INTERNAL MEDICINE, 2013, 158 (10) :779-780
[8]   Fecal Microbiota Transplantation Across the Lifespan: Balancing Efficacy, Safety, and Innovation [J].
Gulati, Ajay S. ;
Nicholson, Maribeth R. ;
Khoruts, Alexander ;
Kahn, Stacy A. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2023, 118 (03) :435-439
[9]   Faecal microbiota transplantation with anti-inflammatory diet (FMT-AID) followed by anti-inflammatory diet alone is effective in inducing and maintaining remission over 1 year in mild to moderate ulcerative colitis: a randomised controlled trial [J].
Kedia, Saurabh ;
Virmani, Shubi ;
Vuyyuru, Sudheer K. ;
Kumar, Peeyush ;
Kante, Bhaskar ;
Sahu, Pabitra ;
Kaushal, Kanav ;
Farooqui, Mariyam ;
Singh, Mukesh ;
Verma, Mahak ;
Bajaj, Aditya ;
Markandey, Manasvini ;
Sachdeva, Karan ;
Das, Prasenjit ;
Makharia, Govind K. ;
Ahuja, Vineet .
GUT, 2022, 71 (12) :2401-+
[10]   Understanding the mechanisms of faecal microbiota transplantation [J].
Khoruts, Alexander ;
Sadowsky, Michael J. .
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2016, 13 (09) :508-516