Mathematical modeling of Dengue virus serotypes propagation in Mexico

被引:3
作者
Sanchez-Gonzalez, Gilberto [1 ]
Conde, Renaud [1 ]
机构
[1] Inst Nacl Salud Publ, Ctr Invest Enfermedades Infecciosas, Cuernavaca, Morelos, Mexico
来源
PLOS ONE | 2023年 / 18卷 / 07期
关键词
AEDES-AEGYPTI DIPTERA; CULICIDAE FEMALES; TRANSMISSION; IMPACT; FEVER; TEMPERATURE; SURVIVAL; FATALITY;
D O I
10.1371/journal.pone.0288392
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The Dengue virus (DENV) constitutes a major vector borne virus disease worldwide. Prediction of the DENV spread dynamics, prevalence and infection rates are crucial elements to guide the public health services effort towards meaningful actions. The existence of four DENV serotypes further complicates the virus proliferation forecast. The different serotypes have varying clinical impacts, and the symptomatology of the infection is dependent on the infection history of the patient. Therefore, changes in the prevalent DENV serotype found in one location have a profound impact on the regional public health. The prediction of the spread and intensity of infection of the individual DENV serotypes in specific locations would allow the authorities to plan local pesticide spray to control the vector as well as the purchase of specific antibody therapy. Here we used a mathematical model to predict serotype-specific DENV prevalence and overall case burden in Mexico.
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页数:13
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