Mass spectrometry-based proteomic applications in dental implants research

被引：2
作者：
Halstenbach, Tim [1 ]
Topitsch, Annika [1 ,2 ,3 ,4 ]
Schilling, Oliver [2 ]
Iglhaut, Gerhard [1 ]
Nelson, Katja [1 ]
Fretwurst, Tobias [1 ,5 ]
机构：
[1] Univ Freiburg, Fac Med, Med Ctr, Dept Oral and Craniomaxillofacial Surg Translat Im, Freiburg, Germany
[2] Univ Freiburg, Inst Surg Pathol, Fac Med, Med Ctr, Freiburg, Germany
[3] Univ Freiburg, Spemann Grad Sch Biol & Med SGBM, Freiburg, Germany
[4] Univ Freiburg, Fac Biol, Freiburg, Germany
[5] Univ Freiburg, Fac Med, Med Ctr, Dept Oral and Craniomaxillofacial Surg Translat Im, Hugstetter Str 55, D-79106 Freiburg, Germany
来源：
PROTEOMICS CLINICAL APPLICATIONS | 2024年 / 18卷 / 03期
关键词：
alveolar bone; dental implants; peri-implant crevicular fluid; peri-implantitis; proteomics; BONE LOSS BIOMARKERS; PERI-IMPLANTITIS; CREVICULAR FLUID; MATRIX METALLOPROTEINASE-8; NATURAL TEETH; GINGIVAL; HEALTH; PERIODONTITIS; EXPRESSION; DISEASE;
D O I：
10.1002/prca.202300019
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Dental implants have been established as successful treatment options for missing teeth with steadily increasing demands. Today, the primary areas of research in dental implantology revolve around osseointegration, soft and hard tissue grafting as well as peri-implantitis diagnostics, prevention, and treatment. This review provides a comprehensive overview of the current literature on the application of MS-based proteomics in dental implant research, highlights how explorative proteomics provided insights into the biology of peri-implant soft and hard tissues and how proteomics facilitated the stratification between healthy and diseased implants, enabling the identification of potential new diagnostic markers. Additionally, this review illuminates technical aspects, and provides recommendations for future study designs based on the current evidence.
引用
收藏
页数：16
相关论文
共 105 条
  • [31] Interleukin - 17 and Interleukin-10 as Inflammatory and Prevention Biomarkers in Periimplant Diseases
    Farhad, Shirin Zahra
    Rezazadeh, Faeze
    Mohammadi, Majid
    [J]. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, 2019, 10
  • [32] Reproducible proteomics sample preparation for single FFPE tissue slices using acid-labile surfactant and direct trypsinization
    Foell, Melanie Christine
    Fahrner, Matthias
    Oria, Victor Oginga
    Kuehs, Markus
    Biniossek, Martin Lothar
    Werner, Martin
    Bronsert, Peter
    Schilling, Oliver
    [J]. CLINICAL PROTEOMICS, 2018, 15
  • [33] Osteogenesis imperfecta
    Forlino, Antonella
    Marini, Joan C.
    [J]. LANCET, 2016, 387 (10028) : 1657 - 1671
  • [34] A prospective study of factors influencing morbidity after iliac crest harvesting for oral onlay grafting
    Fretwurst, T.
    Wanner, L.
    Nahles, S.
    Raguse, J. D.
    Stricker, A.
    Metzger, M. C.
    Nelson, K.
    [J]. JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, 2015, 43 (05) : 705 - 709
  • [35] Proteomic profiling of human bone from different anatomical sites - A pilot study
    Fretwurst, Tobias
    Tritschler, Isabel
    Rothweiler, Rene
    Nahles, Susanne
    Altmann, Brigitte
    Schilling, Oliver
    Nelson, Katja
    [J]. PROTEOMICS CLINICAL APPLICATIONS, 2022, 16 (05)
  • [36] Immunohistological composition of peri-implantitis affected tissue around ceramic implants-A pilot study
    Fretwurst, Tobias
    Mueller, Janina
    Larsson, Lena
    Bronsert, Peter
    Hazard, Derek
    Castilho, Rogerio M.
    Kohal, Ralf
    Nelson, Katja
    Iglhaut, Gerhard
    [J]. JOURNAL OF PERIODONTOLOGY, 2021, 92 (04) : 571 - 579
  • [37] Characterization of macrophages infiltrating peri-implantitis lesions
    Fretwurst, Tobias
    Garaicoa-Pazmino, Carlos
    Nelson, Katja
    Giannobile, William, V
    Squarize, Cristiane H.
    Larsson, Lena
    Castilho, Rogerio M.
    [J]. CLINICAL ORAL IMPLANTS RESEARCH, 2020, 31 (03) : 274 - 281
  • [38] Periodontal disease, peri-implant disease and levels of salivary biomarkers IL-1β, IL-10, RANK, OPG, MMP-2, TGF-β and TNF-α: follow-up over 5 years
    Gomes, Alex Martins
    Douglas-de-Oliveira, Dhelfeson Willya
    Ferreira, Sergio Diniz
    da Silva, Tarcilia Aparecida
    Miranda Cota, Luis Otavio
    Costa, Fernando Oliveira
    [J]. JOURNAL OF APPLIED ORAL SCIENCE, 2019, 27
  • [39] Influence of supragingival biofilm control and smoking habit on Interleukin-1β concentration
    Gomes, Sabrina Carvalho
    Abascal, Carolina Coradini
    Haas, Alex Nogueira
    Melchiors Angst, Patricia Daniela
    Oppermann, Rui Vicente
    Chierici Marcantonio, Rosemary Adriana
    [J]. BRAZILIAN ORAL RESEARCH, 2015, 29 (01): : 1 - 8
  • [40] Formation, collection and significance of gingival crevice fluid
    Griffiths, GS
    [J]. PERIODONTOLOGY 2000, 2003, 31 : 32 - 42
12345678910