Mass spectrometry-based proteomic applications in dental implants research

被引：2
作者：
Halstenbach, Tim [1 ]
Topitsch, Annika [1 ,2 ,3 ,4 ]
Schilling, Oliver [2 ]
Iglhaut, Gerhard [1 ]
Nelson, Katja [1 ]
Fretwurst, Tobias [1 ,5 ]
机构：
[1] Univ Freiburg, Fac Med, Med Ctr, Dept Oral and Craniomaxillofacial Surg Translat Im, Freiburg, Germany
[2] Univ Freiburg, Inst Surg Pathol, Fac Med, Med Ctr, Freiburg, Germany
[3] Univ Freiburg, Spemann Grad Sch Biol & Med SGBM, Freiburg, Germany
[4] Univ Freiburg, Fac Biol, Freiburg, Germany
[5] Univ Freiburg, Fac Med, Med Ctr, Dept Oral and Craniomaxillofacial Surg Translat Im, Hugstetter Str 55, D-79106 Freiburg, Germany
来源：
PROTEOMICS CLINICAL APPLICATIONS | 2024年 / 18卷 / 03期
关键词：
alveolar bone; dental implants; peri-implant crevicular fluid; peri-implantitis; proteomics; BONE LOSS BIOMARKERS; PERI-IMPLANTITIS; CREVICULAR FLUID; MATRIX METALLOPROTEINASE-8; NATURAL TEETH; GINGIVAL; HEALTH; PERIODONTITIS; EXPRESSION; DISEASE;
D O I：
10.1002/prca.202300019
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Dental implants have been established as successful treatment options for missing teeth with steadily increasing demands. Today, the primary areas of research in dental implantology revolve around osseointegration, soft and hard tissue grafting as well as peri-implantitis diagnostics, prevention, and treatment. This review provides a comprehensive overview of the current literature on the application of MS-based proteomics in dental implant research, highlights how explorative proteomics provided insights into the biology of peri-implant soft and hard tissues and how proteomics facilitated the stratification between healthy and diseased implants, enabling the identification of potential new diagnostic markers. Additionally, this review illuminates technical aspects, and provides recommendations for future study designs based on the current evidence.
引用
收藏
页数：16
相关论文
共 105 条
  • [1] Mass spectrometry-based proteomic approaches for salivary protein biomarkers discovery and dental caries diagnosis: A critical review
    Ahmad, Paras
    Hussain, Ahmed
    Siqueira, Walter L.
    [J]. MASS SPECTROMETRY REVIEWS, 2024, 43 (04) : 826 - 856
  • [2] Peri-Implantitis Diagnosis and Prognosis Using Biomarkers in Peri-Implant Crevicular Fluid: A Narrative Review
    Alassy, Hatem
    Parachuru, Praveen
    Wolff, Larry
    [J]. DIAGNOSTICS, 2019, 9 (04)
  • [3] Evaluation of Metalloproteinase-8 Levels in Crevicular Fluid of Patients with Healthy Implants or Periodontitis
    Aleksandrowicz, Pawel
    Zelechowska, Paulina
    Agier, Justyna
    Starska, Katarzyna
    Kedzierski, Krzysztof
    Wysokinska-Miszczuk, Joanna
    Brzezinska-Blaszczyk, Ewa
    [J]. MEDIATORS OF INFLAMMATION, 2017, 2017
  • [4] Matrix metalloproteinase-8 is the major potential collagenase in active peri-implantitis
    Arakawa, Hikaru
    Uehara, Junji
    Hara, Emilio Satoshi
    Sonoyama, Wataru
    Kimura, Aya
    Kanyama, Manabu
    Matsuka, Yoshizo
    Kuboki, Takuo
    [J]. JOURNAL OF PROSTHODONTIC RESEARCH, 2012, 56 (04) : 249 - 255
  • [5] Osteoprotegerin levels in peri-implant crevicular fluid
    Arikan, Fatih
    Buduneli, Nurcan
    Kutukculer, Necil
    [J]. CLINICAL ORAL IMPLANTS RESEARCH, 2008, 19 (03) : 283 - 288
  • [6] Novel protein identification methods for biomarker discovery via a proteomic analysis of periodontally healthy and diseased gingival crevicular fluid samples
    Baliban, Richard C.
    Sakellari, Dimitra
    Li, Zukui
    DiMaggio, Peter A.
    Garcia, Benjamin A.
    Floudas, Christodoulos A.
    [J]. JOURNAL OF CLINICAL PERIODONTOLOGY, 2012, 39 (03) : 203 - 212
  • [7] Evaluation of Periimplant Crevicular Fluid Prostaglandin E2 and Matrix Metalloproteinase-8 Levels From Health to Periimplant Disease Status: A Prospective Study
    Basegmez, Cansu
    Yalcin, Serdar
    Yalcin, Funda
    Ersanli, Selim
    Mijiritsky, Eitan
    [J]. IMPLANT DENTISTRY, 2012, 21 (04) : 306 - 310
  • [8] Evaluation of Data-Dependent and -Independent Mass Spectrometric Workflows for Sensitive Quantification of Proteins and Phosphorylation Sites
    Bauer, Manuel
    Ahrne, Erik
    Baron, Anna P.
    Glatter, Timo
    Fava, Luca L.
    Santamaria, Anna
    Nigg, Erich A.
    Schmidt, Alexander
    [J]. JOURNAL OF PROTEOME RESEARCH, 2014, 13 (12) : 5973 - 5988
  • [9] Proteomic and N-Terminomic TAILS Analyses of Human Alveolar Bone Proteins: Improved Protein Extraction Methodology and LysargiNase Digestion Strategies Increase Proteome Coverage and Missing Protein Identification
    Bell, Peter A.
    Solis, Nestor
    Kizhakkedathu, Jayachandran N.
    Matthew, Ian
    Overall, Christopher M.
    [J]. JOURNAL OF PROTEOME RESEARCH, 2019, 18 (12) : 4167 - 4179
  • [10] Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions
    Berglundh, Tord
    Armitage, Gary
    Araujo, Mauricio G.
    Avila-Ortiz, Gustavo
    Blanco, Juan
    Camargo, Paulo M.
    Chen, Stephen
    Cochran, David
    Derks, Jan
    Figuero, Elena
    Hammerle, Christoph H. F.
    Heitz-Mayfield, Lisa J. A.
    Guy Huynh-Ba
    Iacono, Vincent
    Koo, Ki-Tae
    Lambert, France
    McCauley, Laurie
    Quirynen, Marc
    Renvert, Stefan
    Salvi, Giovanni E.
    Schwarz, Frank
    Tarnow, Dennis
    Tomasi, Cristiano
    Wang, Hom-Lay
    Zitzmann, Nicola
    [J]. JOURNAL OF CLINICAL PERIODONTOLOGY, 2018, 45 : S286 - S291
12345678910