Auxin promotes hypocotyl elongation by enhancing BZR1 nuclear accumulation in Arabidopsis

被引：42

作者：

Yu, Zipeng ^{[1
]}

Ma, Jinxin ^{[1
]}

Zhang, Mengyue ^{[1
]}

Li, Xiaoxuan ^{[1
]}

Sun, Yi ^{[1
]}

Zhang, Mengxin ^{[1
]}

Ding, Zhaojun ^{[1
]}

机构：

[1] Shandong Univ, Sch Life Sci, Key Lab Plant Dev & Environm Adaptat Biol, Minist Educ, Qingdao, Shandong, Peoples R China

来源：

SCIENCE ADVANCES | 2023年 / 9卷 / 01期

基金：

中国国家自然科学基金;

关键词：

PROTEIN-KINASE CASCADES; GENE-EXPRESSION; INDUCED GROWTH; LIGHT CONTROL; PLANT-GROWTH; CELL; PHOSPHORYLATION; BIOSYNTHESIS; ACTIVATION; MUTATIONS;

D O I：

10.1126/sciadv.ade2493

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Auxin and brassinosteroids (BRs) are two major growth-promoting phytohormones that shape hypocotyl elon-gation; however, the cross-talk between auxin and BR in this process is not fully understood. In this study, we found that auxin-induced hypocotyl elongation is dependent on brassinazole-resistant 1 (BZR1), a core BR sig-naling component. Auxin promotes BZR1 nuclear accumulation in hypocotyl cells, a process dependent on mitogen-activated protein kinase 3 (MPK3) and MPK6, which are both activated by auxin and whose encoding genes are highly expressed in hypocotyls. We determined that MPK3/MPK6 phosphorylate and reduce the protein stability of general regulatory factor 4 (GRF4), a member of the 14-3-3 family of proteins that retain BZR1 in the cytoplasm. In summary, this study reveals the molecular mechanism by which auxin promotes hy-pocotyl elongation by enhancing BZR1 nuclear accumulation via MPK3/MPK6-regulated GRF4 protein stability.

引用

页数：15

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