Anaplasmosis-Induced Hemophagocytic Lymphohistiocytosis: A Case Report and Review of the Literature

被引：5

作者：

Scribner, Jacob ^{[1
,3
]}

Wu, Benita ^{[2
]}

Lamyaithong, Andre ^{[2
]}

Arcega, Victor ^{[1
]}

Villanueva, Daphne-Dominique ^{[1
,3
]}

机构：

[1] West Virginia Univ, Dept Med Sect Infect Dis, Morgantown, WV USA

[2] West Virginia Univ, Dept Internal Med, Morgantown, WV USA

[3] West Virginia Univ, Dept Med, Sect Infect Dis, 64 Med Ctr Dr,POB 9163, Morgantown, WV 26506 USA

来源：

OPEN FORUM INFECTIOUS DISEASES | 2023年 / 10卷 / 05期

关键词：

Anaplasma phagocytophilum; anaplasmosis; hemophagocytic lymphohistiocytosis; tick-borne; EPIDEMIOLOGY; EHRLICHIOSIS; DIAGNOSIS; TICKS;

D O I：

10.1093/ofid/ofad213

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cases of anaplasmosis have increased steadily and are appearing in states where it is less common. While symptoms are usually mild, in rare cases it can cause hemophagocytic lymphohistiocytosis. Here, we present a case of polymerase chain reaction-confirmed Anaplasma phagocytophilum with morulae on peripheral blood smear associated with biopsy-proven hemophagocytic lymphohistiocytosis. A 78-year old man presented one month after a tick bite with fever and lab findings consistent with hemophagocytic lymphohistiocytosis. Morulae were visualized in the bone marrow biopsy and serum PCR confirmed Anaplasma phagocytophilum. He improved on doxycycline and steroids.

引用

页数：5

共 30 条

[1] Anaplasmosis with associated haemophagocytic lymphohistiocytosis [J].