Uses of Polypodium leucotomos Extract in Oncodermatology

被引：7

作者：

Calzari, Paolo ^{[1
]}

Vaienti, Silvia ^{[2
]}

Nazzaro, Gianluca ^{[1
,3
]}

机构：

[1] Univ Milan, Dept Pathophysiol & Transplantat, I-20122 Milan, Italy

[2] Univ Verona, Dept Med, Sect Dermatol & Venereol, I-30127 Verona, Italy

[3] CaGranda Osped Maggiore Policlin, Fdn IRCCS, Unit Dermatol, Via Pace 9, I-20122 Milan, Italy

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 02期

关键词：

chemoprevention; cancer; cell death; metabolism; cell invasion; metastasis; CIS-UROCANIC ACID; INDUCED SYSTEMIC SUPPRESSION; ULTRAVIOLET-B; PHOTOPROTECTIVE PROPERTIES; CONTACT HYPERSENSITIVITY; PHOTODYNAMIC THERAPY; HYDROPHILIC EXTRACT; LANGERHANS CELLS; CHLOROGENIC ACID; CAFFEIC ACID;

D O I：

10.3390/jcm12020673

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effects of UV radiation on the skin and its damage mechanisms are well known. New modalities of exogenous photoprotection have been studied. It was demonstrated that Polypodium leucotomos extract acts as an antioxidant, photoprotectant, antimutagenic, anti-inflammatory, and immunoregulator. It is effective when taken orally and/or applied topically to support the prevention of skin cancers. It also has an important role in preventing photoaging. This review aims to report the mechanisms through which Polypodium leucotomos acts and to analyze its uses in oncodermatology with references to in vitro and in vivo studies. Additionally, alternative uses in non-neoplastic diseases, such as pigmentary disorders, photosensitivity, and atopic dermatitis, have been considered.

引用

页数：12

共 90 条

[1] Booster Effect of a Natural Extract of Polypodium leucotomos (Fernblock®) That Improves the UV Barrier Function and Immune Protection Capability of Sunscreen Formulations [J].