One-Carbon Homologation of α,β-Unsaturated Aldehydes: Access to α-Tertiary β,γ-Unsaturated Aldehydes

被引：2

作者：

Delbrassinne, Arnaud ^{[1
]}

Mba, Boris Junior Takam ^{[1
]}

Collard, Laurent ^{[1
]}

Robiette, Raphael ^{[1
]}

机构：

[1] Catholic Univ Louvain, Inst Condensed Matter & Nanosci, Pl Louis Pasteur 1 Box L4-01-02, B-1348 Louvain La Neuve, Belgium

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 26卷 / 40期

关键词：

Epoxide; Homologation; Meinwald; Migration; Rearrangement; MEDIATED ASYMMETRIC EPOXIDATIONS; SELECTIVE HYDROFORMYLATION; REARRANGEMENT; EPOXIDES; OXIDATION;

D O I：

10.1002/ejoc.202300765

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient protocol for the synthesis of enolizable alpha-substituted beta,gamma-unsaturated aldehydes is reported. The developed strategy involves two steps, epoxidation and Meinwald rearrangement, to result in a one-carbon homologation of alpha,beta-unsaturated aldehydes enabling the insertion of a CHR unit.

引用

页数：5

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