Prospective Evaluation of SARS-CoV-2 Rapid Antigen Test for Screening of Asymptomatic Caregivers

被引：0

作者：

Park, Kuenyoul ^{[1
,2
]}

Sung, Heungsup ^{[1
,3
]}

Kim, Mi-Na ^{[1
,3
]}

机构：

[1] Univ Ulsan Coll Med, Asan Med Ctr, Dept Lab Med, Seoul, South Korea

[2] Inje Univ Coll Med, Sanggye Paik Hosp, Dept Lab Med, Seoul, South Korea

[3] 88 Olympic Ro,43 Gil, Seoul 05505, South Korea

来源：

CLINICAL LABORATORY | 2023年 / 69卷 / 03期

关键词：

SARS-CoV-2; COVID-19; rapid antigen test; screening; asymptomatic; caregiver; VARIANTS;

D O I：

10.7754/Clin.Lab.2022.220644

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Background: This study aimed to assess clinical performance of a rapid antigen test (RAT) for screening asymptomatic patients during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron outbreak.Methods: RAT with the routine real-time reverse transcription-polymerase chain reaction (rRT-PCR) using the same nasopharyngeal swab in universal transport medium was performed for rapid screening of asymptomatic caregivers of emergent patients from March to April 2022 in a tertiary-care hospital in Korea. Clinical performance of RAT compared to that analyzed by rRT-PCR was evaluated.Results: A total of 900 caregivers were enrolled in this study, of which 14 (1.6%) were RAT-positive and 44 (5.0%) were positive for rRT-PCR. Overall sensitivity and specificity of RAT were 31.8% and 100.0%, respectively.Conclusions: Caution must be taken when using RAT as a screening test for asymptomatic caregivers as this may lead to outbreaks among high-risk patients.

引用

收藏

页码：609 / 613

页数：5

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