Enantioselective total syntheses of six natural and two proposed meroterpenoids from Psoralea corylifolia

被引：6
作者：
Chen, Xiao-Wei [1 ]
Hou, Zi-Chao [1 ]
Chen, Chi [1 ]
Zhang, Ling-Hui [1 ]
Chen, Meng-En [1 ]
Zhang, Fu-Min [1 ,2 ]
机构：
[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] East China Normal Univ, Shanghai Engn Res Ctr Mol Therapeut & New Drug Dev, Sch Chem & Mol Engn, Shanghai 200062, Peoples R China
来源：
CHEMICAL SCIENCE | 2023年 / 14卷 / 21期
关键词：
CHEMICAL-CONSTITUENTS; IRON(III) CHLORIDE; CARBONYL-COMPOUNDS; CONSTRUCTION; ECONOMY; CONDENSATION; DERIVATIVES; ARYLATION; KETONES; ARENES;
D O I：
10.1039/d3sc00582h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first enantioselective total syntheses of six natural and two proposed meroterpenoids isolated from Psoralea corylifolia have been achieved in 7-9 steps from 2-methylcyclohexanone. The current synthetic approaches feature a high level of synthetic flexibility, stereodivergent fashion and short synthetic route, thereby providing a potential platform for the preparation of numerous this-type meroterpenoids and their pseudo-natural products.
引用
收藏
页码：5699 / 5704
页数：6
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