Enantioselective total syntheses of six natural and two proposed meroterpenoids from Psoralea corylifolia

被引：6

作者：

Chen, Xiao-Wei ^{[1
]}

Hou, Zi-Chao ^{[1
]}

Chen, Chi ^{[1
]}

Zhang, Ling-Hui ^{[1
]}

Chen, Meng-En ^{[1
]}

Zhang, Fu-Min ^{[1
,2
]}

机构：

[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

[2] East China Normal Univ, Shanghai Engn Res Ctr Mol Therapeut & New Drug Dev, Sch Chem & Mol Engn, Shanghai 200062, Peoples R China

来源：

CHEMICAL SCIENCE | 2023年 / 14卷 / 21期

关键词：

CHEMICAL-CONSTITUENTS; IRON(III) CHLORIDE; CARBONYL-COMPOUNDS; CONSTRUCTION; ECONOMY; CONDENSATION; DERIVATIVES; ARYLATION; KETONES; ARENES;

D O I：

10.1039/d3sc00582h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first enantioselective total syntheses of six natural and two proposed meroterpenoids isolated from Psoralea corylifolia have been achieved in 7-9 steps from 2-methylcyclohexanone. The current synthetic approaches feature a high level of synthetic flexibility, stereodivergent fashion and short synthetic route, thereby providing a potential platform for the preparation of numerous this-type meroterpenoids and their pseudo-natural products.

引用

页码：5699 / 5704

页数：6

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