A 20-year trend of prevalence and susceptibility to trimethoprim/sulfamethoxazole of Stenotrophomonas maltophilia in a single secondary care hospital in Korea

被引：5

作者：

Song, Je Eun ^{[1
]}

Kim, Sollip ^{[2
]}

Kwak, Yee Gyung ^{[1
]}

Shin, Sunghwan ^{[3
]}

Um, Tae-Hyun ^{[3
]}

Cho, Chong Rae ^{[3
]}

Chang, Jeonghyun ^{[3
]}

机构：

[1] Inje Univ, Infect Dis Internal Med, Ilsan Paik Hosp, Goyang, South Korea

[2] Univ Ulsan, Asan Med Ctr, Dept Lab Med, Coll Med, Seoul, South Korea

[3] Inje Univ, Dept Lab Med, Ilsan Paik Hosp, 170 Juhwa Ro, Goyang 10380, Gyeonggi Do, South Korea

来源：

MEDICINE | 2023年 / 102卷 / 04期

关键词：

antimicrobials; epidemiology; Stenotrophomonas maltophilia; susceptibility; trend; trimethoprim; sulfamethoxazole; ANTIMICROBIAL SUSCEPTIBILITY; TRIMETHOPRIM-SULFAMETHOXAZOLE; SURVEILLANCE; RESISTANCE; INFECTION; XANTHOMONAS; PNEUMONIA; PROGRAM; SOCIETY; GENUS;

D O I：

10.1097/MD.0000000000032704

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Stenotrophomonas maltophilia is a Gram-negative opportunistic pathogen that can cause serious infection. We aimed to analyze the prevalence and susceptibility rates to trimethoprim/sulfamethoxazole of S. maltophilia. We conducted a retrospective study of S. maltophilia isolates from a university hospital from 2001 to 2020. Clinical information, the numbers of isolates and susceptibility rates were analyzed by year. Susceptibility rates and changes in respiratory and non-respiratory samples were compared. 1805 S. maltophilia isolates were identified, of which 81.4% (1469/1805) were from respiratory samples. There was a male predominance and 52% of the isolates were from general wards. The average susceptibility rate was 87.7% and there was no significant annual trend (P = .519). The susceptibility rate was 88.7% in respiratory samples and 84.1% in non-respiratory samples (P = .018). Susceptibility analyses using clinical data over long periods can guide the choice of antimicrobials especially for pathogen whose treatment options are limited.

引用

页数：5

共 34 条

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