Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious Diseases: A Comprehensive Review

被引：115
作者：
Al-Qahtani, Arwa A. [1 ]
Alhamlan, Fatimah S. [2 ,3 ]
Al-Qahtani, Ahmed Ali [2 ,3 ]
机构：
[1] Al Imam Mohammad Ibn Saud Islamic Univ, Coll Med, Dept Family Med, Riyadh 11432, Saudi Arabia
[2] King Faisal Specialist Hosp & Res Ctr, Dept Infect & Immun, Riyadh 11211, Saudi Arabia
[3] Alfaisal Univ, Coll Med, Dept Microbiol & Immunol, Riyadh 11211, Saudi Arabia
来源：
TROPICAL MEDICINE AND INFECTIOUS DISEASE | 2024年 / 9卷 / 01期
关键词：
interleukins; infectious diseases; pro-inflammatory; anti-inflammatory; immune response; diagnosis; therapy; REGULATORY T-CELLS; IFN-GAMMA; IL-10; IMMUNITY; INNATE; PROGRESSION; INHIBITION; RESPONSES; DEFENSE; SEPSIS;
D O I：
10.3390/tropicalmed9010013
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment of immune cells, whereas anti-inflammatory ILs help to suppress excessive inflammation and promote tissue repair. Here, we provide a comprehensive overview of the role of pro-inflammatory and anti-inflammatory ILs in infectious diseases, with a focus on the mechanisms underlying their effects, their diagnostic and therapeutic potential, and emerging trends in IL-based therapies.
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页数：20
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