Analysis of the factors influencing male infertility of reproductive age in Jinan

被引:0
作者
Li, S. [1 ]
Shen, X. [1 ]
Qin, X. -X. [2 ]
Fang, S. [3 ]
Chen, J. [1 ]
Yang, H. -J. [3 ,4 ]
机构
[1] Shandong Univ, Cheeloo Coll Med, Sch Publ Hlth, Dept Maternal & Child Hlth, Jinan, Shandong, Peoples R China
[2] Binzhou Med Univ, Sch Publ Hlth & Management, Binzhou, Peoples R China
[3] Shandong Prov Maternal & Child Hlth Care Hosp, Key Lab Birth Regulat & Control Technol, Natl Hlth Commiss China, Jinan, Peoples R China
[4] Jinan Med Ctr Management, Jinan, Peoples R China
关键词
Infertility; Influencing factors; Case-control study;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
OBJECTIVE: The World Health Organization (WHO) defines infertility as a person failing to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse. Infertility includes female infertility and male in-fertility. The aim of this paper is to study the etiology of infertility and related influencing factors in men of reproductive age in Jinan.PATIENTS AND METHODS: In this study, 172 male infertile patients who attended the Department of Assisted Reproduction of Shandong Provincial Maternal and Child Health Hospital in Shandong, China and the Infertility Clinic of Jinan Central Hospital in Shandong, China from August 2021 to April 2022 are selected as the study population (infertility group). A convenience sampling method is used to select 257 men from couples attending the Obstetrics Department of Qilu Hospital in Shandong, China, the Obstetrics Department of the Second Hospital of Shandong University in Shandong, China, and the Obstetrics Department of Maternal and Child Health Hospi-tal in Shandong, China from October 2021 to February 2022 as the study subjects (control group). A self-designed questionnaire is used to conduct the survey, which includes basic personal information, lifestyle information, marital and familyrelated information, and one-way and multi-way logistic regression analyses are performed. RESULTS: The average age of the case group and the control group are 34.03 +/- 5.13 years old and 33.61 +/- 8.18 years old; the average height is 175.80 +/- 5.91 cm and 176.78 +/- 5.25 cm; the aver-age weight is 80.28 +/- 14.70 kg and 83.09 +/- 45.36 kg. The differences in age, height, and weight between the case group and the control group are not statistically significant by t-test. Moderate oligospermia is the predominant cause of in-fertility in men of reproductive age in Jinan. A multifactorial logistic regression analysis yields that academic qualifications (OR=2.518, 95% CI: 1.023 to 6.196), coffee consumption (OR=7.692,95% CI: 1.623 to 36.460), living in a room that had been renovated within a period of time (OR=2.769, 95% CI: 1.104 to 6.949), stress level (OR=47.280, 95% CI: 23.656-94.494), quality of sexual life (OR=3.352, 95% CI: 1.331-8.442), and duration of couple separation (OR=3.851, 95% CI: 1.094-13.557) are the main risk factors for in-fertility in men of reproductive age in Jinan.CONCLUSIONS: In this study, a total of 6 risk factors are screened for male infertility in Ji-nan in the reproductive age, including high academic qualifications, coffee consumption, living in a room that has finished renovation within 3 months, high stress, poor quality of sexual life, and long spousal separation. Three factors can be controlled, avoided, or reduced through personal actions; the factors are coffee consumption, living in a room that has finished renovation within 3 months, and high stress, all of which may reduce the level of male reproductive health.
引用
收藏
页码:7092 / 7100
页数:9
相关论文
共 26 条
[1]  
Adelusi B, 1998, Afr J Med Med Sci, V27, P47
[2]   A unique view on male infertility around the globe [J].
Agarwal, Ashok ;
Mulgund, Aditi ;
Hamada, Alaa ;
Chyatte, Michelle Renee .
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2015, 13
[3]   Psychological stress, stressful life events, male factor infertility, and testicular function: a cross-sectional study [J].
Brauner, Elvira V. ;
Nordkap, Loa ;
Priskorn, Laerke ;
Hansen, Ase Marie ;
Bang, Anne Kirstine ;
Holmboe, Stine A. ;
Schmidt, Lone ;
Jensen, Tina K. ;
Jorgensen, Niels .
FERTILITY AND STERILITY, 2020, 113 (04) :865-875
[4]   Relationship between caffeine intake and infertility: a systematic review of controlled clinical studies [J].
Bu, Fan-Long ;
Feng, Xue ;
Yang, Xiao-Ying ;
Ren, Jun ;
Cao, Hui-Juan .
BMC WOMENS HEALTH, 2020, 20 (01)
[5]  
Cannarella R, 2019, EUR REV MED PHARMACO, V23, P3112, DOI 10.26355/eurrev_201904_17595
[6]  
Chandra Anjani, 2014, Natl Health Stat Report, P1
[7]  
Chinese Population Association, China infertility status survey report 2018
[8]  
Güngör K, 2022, EUR REV MED PHARMACO, V26, P499, DOI 10.26355/eurrev_202201_27875
[9]   Formaldehyde Exposure Induces Autophagy in Testicular Tissues of Adult Male Rats [J].
Han, Shui-Ping ;
Zhou, Dang-Xia ;
Lin, Pu ;
Qin, Zhen ;
An, Lu ;
Zheng, Lie-Rui ;
Lei, Li .
ENVIRONMENTAL TOXICOLOGY, 2015, 30 (03) :323-331
[10]   Lifestyle and fertility: the influence of stress and quality of life on male fertility [J].
Ilacqua, Alessandro ;
Izzo, Giulia ;
Emerenziani, Gian Pietro ;
Baldari, Carlo ;
Aversa, Antonio .
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2018, 16