Plant transbilayer lipid asymmetry and the role of lipid flippases

被引：1
|
作者：
Villagrana, Richard [1 ]
Lopez-Marques, Rosa Laura [1 ]
机构：
[1] Univ Copenhagen, Dept Plant & Environm Sci, Thorvaldsensvej 40, DK-1871 Frederiksberg C, Denmark
来源：
EMERGING TOPICS IN LIFE SCIENCES | 2023年 / 7卷 / 01期
关键词：
PLASMA-MEMBRANE; THYLAKOID MEMBRANES; INTACT CHLOROPLASTS; CHILLING TOLERANCE; ENVELOPE MEMBRANES; KEY PLAYERS; ANNEXIN-V; ARABIDOPSIS; PHOSPHATIDYLCHOLINE; CELLS;
D O I：
10.1042/ETLS20220083
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Many biological membranes present an asymmetric lipid distribution between the two leaflets that is known as the transbilayer lipid asymmetry. This asymmetry is essential for cell survival and its loss is related to apoptosis. In mammalian and yeast cells, ATP dependent transport of lipids to the cytosolic side of the biological membranes, carried out by so-called lipid flippases, contributes to the transbilayer lipid asymmetry. Most of these lipid flippases belong to the P4-ATPase protein family, which is also present in plants. In this review, we summarize the relatively scarce literature concerning the presence of transbilayer lipid asymmetry in different plant cell membranes and revise the potential role of lipid flippases of the P4-ATPase family in generation and/or maintenance of this asymmetry.
引用
收藏
页码：21 / 29
页数：9
相关论文
共 50 条
  • [1] Transbilayer lipid asymmetry
    Kobayashi, Toshihide
    Menon, Anant K.
    CURRENT BIOLOGY, 2018, 28 (08) : R386 - R391
  • [2] Dynamic Transbilayer Lipid Asymmetry
    van Meer, Gerrit
    COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2011, 3 (05): : 1 - 11
  • [3] Flippases, floppases, and scramblases: Regulators of transbilayer lipid organization.
    Daleke, DL
    BIOPHYSICAL JOURNAL, 2001, 80 (01) : 31A - 31A
  • [4] The role of lipid flippases in bile formation
    Paulusma, Coen C.
    ACTA PHYSIOLOGICA, 2015, 215 : 65 - 66
  • [5] Lipid flippases as key players in plant adaptation to their environment
    Lopez-Marques, Rosa L.
    NATURE PLANTS, 2021, 7 (09) : 1188 - 1199
  • [6] Lipid flippases as key players in plant adaptation to their environment
    Rosa L. López-Marqués
    Nature Plants, 2021, 7 : 1188 - 1199
  • [7] Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol
    Liu S.-L.
    Sheng R.
    Jung J.H.
    Wang L.
    Stec E.
    O'Connor M.J.
    Song S.
    Bikkavilli R.K.
    Winn R.A.
    Lee D.
    Baek K.
    Ueda K.
    Levitan I.
    Kim K.-P.
    Cho W.
    Nature Chemical Biology, 2017, 13 (3) : 268 - 274
  • [8] Generation and maintenance of plasma membrane transbilayer phospholipid asymmetry in health and disease: Role of flippases, floppases, and scramblases
    Daleke, David L.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [9] Lipid specificity of candidate flippases
    Paterson, J
    Zimmerman, M
    Lyles, J
    Lee, CW
    Halleck, M
    Williamson, P
    Schlegel, R
    Daleke, D
    BIOPHYSICAL JOURNAL, 2001, 80 (01) : 256A - 256A
  • [10] Lipid flippases and their biological functions
    Pomorski, T.
    Menon, A. K.
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2006, 63 (24) : 2908 - 2921
12345