Perinatal HIV exposure and infection and caregiver depressive symptoms

被引:2
作者
Brewer, Sarah K. [1 ]
Talge, Nicole [1 ]
Holzman, Claudia [1 ]
Sikorskii, Alla [2 ]
Ezeamama, Amara [2 ,3 ]
机构
[1] Michigan State Univ, Dept Epidemiol & Biostat, E Lansing, MI USA
[2] Michigan State Univ, Dept Psychiat, E Lansing, MI USA
[3] Michigan State Univ, Dept Psychiat, 909 Wilson Rd, E Lansing, MI 48824 USA
来源
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV | 2024年 / 36卷 / 02期
关键词
Perinatal; HIV; AIDS; caregiver depression; sub-saharan Africa; SOCIAL SUPPORT; CHILDREN; DISORDERS; HIV/AIDS; ANXIETY; WOMEN; LIFE;
D O I
10.1080/09540121.2023.2214865
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Survival is possible for children perinatally exposed to or infected by HIV in the post-combined antiretroviral therapy era and identifying factors affecting children's ability to thrive has public health significance. Caregiver mental health is one such factor to consider given its impact on child development, but previous work has not included a full complement of HIV exposure/infection groups within HIV-endemic settings. We compared depressive symptoms among caregivers of 3 groups of 6-10-year-olds in Uganda: children with perinatally acquired HIV infection (CPHIV, n = 102), children with perinatal HIV exposure, but no infection (CPHEU, n = 101), and children without perinatal HIV exposure or infection (CHUU, n = 103). The Hopkins Symptom Checklist was used to assess caregiver depressive symptoms. Generalized linear models were used to estimate group mean differences. Adjusted models included caregiver demographics, social support, and lifetime trauma. Depression symptoms were higher among CPHEU compared to CPHIV caregivers (model coefficient [B] = -3.5, 95%CI -5.3, -1.8). This finding was minimally attenuated following adjustment for covariates (B = -2.2, 95%CI -4.1, -0.4) and among biological mothers. At lower levels of social support and wealth, CPHEU caregivers reported higher levels of depression symptoms than CPHIV caregivers. Our findings point to unmet mental health needs among CPHEU caregivers.
引用
收藏
页码:280 / 290
页数:11
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