Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease

被引：6

作者：

Tonet, Elisabetta ^{[1
]}

Boccadoro, Alberto ^{[1
]}

Micillo, Marco ^{[1
]}

Cocco, Marta ^{[1
]}

Cossu, Alberto ^{[2
]}

Pompei, Graziella ^{[1
]}

Giganti, Melchiore ^{[2
]}

Campo, Gianluca ^{[1
]}

机构：

[1] Azienda Osped Univ Ferrara, Cardiovasc Inst, I-44124 Cona, Italy

[2] Univ Ferrara, Dept Morphol Surg & Expt Med, Sect Radiol, I-44121 Ferrara, Italy

来源：

LIFE-BASEL | 2023年 / 13卷 / 05期

关键词：

coronary CTA; epicardial fat; plaque features; late iodine enhancement; EPICARDIAL ADIPOSE-TISSUE; MYOCARDIAL DELAYED ENHANCEMENT; CARDIOVASCULAR RISK-FACTORS; NAPKIN-RING SIGN; PLAQUE CHARACTERISTICS; CT ANGIOGRAPHY; ATRIAL-FIBRILLATION; LEAMAN SCORE; INFARCTION; FAT;

D O I：

10.3390/life13051086

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Nowadays, coronary computed tomography angiography (CCTA) has a role of paramount importance in the diagnostic algorithm of ischemic heart disease (IHD), both in stable coronary artery disease (CAD) and acute chest pain. Alongside the quantification of obstructive coronary artery disease, the recent technologic developments in CCTA provide additional relevant information that can be considered as "novel markers" for risk stratification in different settings, including ischemic heart disease, atrial fibrillation, and myocardial inflammation. These markers include: (i) epicardial adipose tissue (EAT), associated with plaque development and the occurrence of arrhythmias; (ii) late iodine enhancement (LIE), which allows the identification of myocardial fibrosis; and (iii) plaque characterization, which provides data about plaque vulnerability. In the precision medicine era, these emerging markers should be integrated into CCTA evaluation to allow for the bespoke interventional and pharmacological management of each patient.

引用

页数：15

共 92 条

[1] Lesion-Specific and Vessel-Related Determinants of Fractional Flow Reserve Beyond Coronary Artery Stenosis [J].

Ahmadi, Amir ;

Leipsic, Jonathon ;

Ovrehus, Kristian A. ;

Gaur, Sara ;

Bagiella, Emilia ;

Ko, Brian ;

Dey, Damini ;

LaRocca, Gina ;

Jensen, Jesper M. ;

Botker, Hans Erik ;

Achenbach, Stephan ;

De Bruyne, Bernard ;

Norgaard, Bjarne L. ;

Narula, Jagat .

JACC-CARDIOVASCULAR IMAGING, 2018, 11 (04) :521-530

[2] Delayed contrast-enhanced computed tomography in patients with known or suspected cardiac sarcoidosis: A feasibility study [J].

Aikawa, Tadao ;

Oyama-Manabe, Noriko ;

Naya, Masanao ;

Ohira, Hiroshi ;

Sugimoto, Ayako ;

Tsujino, Ichizo ;

Obara, Masahiko ;

Manabe, Osamu ;

Kudo, Kohsuke ;

Tsutsui, Hiroyuki ;

Tamaki, Nagara .

EUROPEAN RADIOLOGY, 2017, 27 (10) :4054-4063

[3] Does coronary CT angiography improve risk stratification over coronary calcium scoring in symptomatic patients with suspected coronary artery disease? Results from the prospective multicenter international CONFIRM registry [J].

Al-Mallah, Mouaz H. ;

Qureshi, Waqas ;

Lin, Fay Y. ;

Achenbach, Stephan ;

Berman, Daniel S. ;

Budoff, Matthew J. ;

Callister, Tracy Q. ;

Chang, Hyuk-Jae ;

Cademartiri, Filippo ;

Chinnaiyan, Kavitha ;

Chow, Benjamin J. W. ;

Cheng, Victor Y. ;

DeLago, Augustin ;

Gomez, Millie ;

Hadamitzky, Martin ;

Hausleiter, Joerg ;

Kaufmann, Philipp A. ;

Leipsic, Jonathon ;

Maffei, Erica ;

Raff, Gilbert ;

Shaw, Leslee J. ;

Villines, Todd C. ;

Cury, Ricardo C. ;

Feuchtner, Gudrun ;

Plank, Fabian ;

Kim, Yong-Jin ;

Dunning, Allison M. ;

Min, James K. .

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 2014, 15 (03) :267-274

[4] Epicardial adipose tissue and coronary artery plaque characteristics [J].

Alexopoulos, Nikolaos ;

McLean, Dalton S. ;

Janik, Matthew ;

Arepalli, Chesnal D. ;

Stillman, Arthur E. ;

Raggi, Paolo .

ATHEROSCLEROSIS, 2010, 210 (01) :150-154

[5] Coronary Plaque Features on CTA Can Identify Patients at Increased Risk of Cardiovascular Events [J].

Andreini, Daniele ;

Magnoni, Marco ;

Conte, Edoardo ;

Masson, Serge ;

Mushtaq, Saima ;

Berti, Sergio ;

Canestrari, Mauro ;

Casolo, Giancarlo ;

Gabrielli, Domenico ;

Latini, Roberto ;

Marraccini, Paolo ;

Moccetti, Tiziano ;

Modena, Maria Grazia ;

Pontone, Gianluca ;

Gorini, Marco ;

Maggioni, Aldo P. ;

Maseri, Attilio .

JACC-CARDIOVASCULAR IMAGING, 2020, 13 (08) :1704-1717

[6] Long-term prognostic impact of CT-Leaman score in patients with non-obstructive CAD: Results from the COronary CT Angiography EvaluatioN For Clinical Outcomes InteRnational Multicenter (CONFIRM) study [J].

Andreini, Daniele ;

Pontone, Gianluca ;

Mushtaq, Saima ;

Gransar, Heidi ;

Conte, Edoardo ;

Bartorelli, Antonio L. ;

Pepi, Mauro ;

Opolski, Maksymilian P. ;

Hartaigh, Briain O. ;

Berman, Daniel S. ;

Budoff, Matthew J. ;

Achenbach, Stephan ;

Al-Mallah, Mouaz ;

Cademartiri, Filippo ;

Callister, Tracy Q. ;

Chang, Hyuk-Jae ;

Chinnaiyan, Kavitha ;

Chow, Benjamin J. W. ;

Cury, Ricardo ;

Delago, Augustin ;

Hadamitzky, Martin ;

Hausleiter, Joerg ;

Feuchtner, Gudrun ;

Kim, Yong-Jin ;

Kaufmann, Philipp A. ;

Leipsic, Jonathon ;

Lin, Fay Y. ;

Maffei, Erica ;

Raff, Gilbert ;

Shaw, Leslee J. ;

Villines, Todd C. ;

Dunning, Allison ;

Marques, Hugo ;

Rubinshtein, Ronen ;

Hindoyan, Niree ;

Gomez, Millie ;

Min, Jmaes K. .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2017, 231 :18-25

[7] Epicardial adipose tissue and cardiovascular diseases [J].

Ansaldo, Anna Maria ;

Montecucco, Fabrizio ;

Sahebkar, Amirhossein ;

Dallegri, Franco ;

Carbone, Federico .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2019, 278 :254-260

[8] Detecting human coronary inflammation by imaging perivascular fat [J].

Antonopoulos, Alexios S. ;

Sanna, Fabio ;

Sabharwal, Nikant ;

Thomas, Sheena ;

Oikonomou, Evangelos K. ;

Herdman, Laura ;

Margaritis, Marios ;

Shirodaria, Cheerag ;

Kampoli, Anna-Maria ;

Akoumianakis, Ioannis ;

Petrou, Mario ;

Sayeed, Rana ;

Krasopoulos, George ;

Psarros, Constantinos ;

Ciccone, Patricia ;

Brophy, Carl M. ;

Digby, Janet ;

Kelion, Andrew ;

Uberoi, Raman ;

Anthony, Suzan ;

Alexopoulos, Nikolaos ;

Tousoulis, Dimitris ;

Achenbach, Stephan ;

Neubauer, Stefan ;

Channon, Keith M. ;

Antoniades, Charalambos .

SCIENCE TRANSLATIONAL MEDICINE, 2017, 9 (398)

[9] The Incremental Role of Coronary Computed Tomography in Chronic Coronary Syndromes [J].

Baessato, Francesca ;

Guglielmo, Marco ;

Muscogiuri, Giuseppe ;

Baggiano, Andrea ;

Fusini, Laura ;

Scafuri, Stefano ;

Babbaro, Mario ;

Mollace, Rocco ;

Collevecchio, Ada ;

Guaricci, Andrea, I ;

Rabbat, Mark ;

D'Andrea, Antonello ;

Pontone, Gianluca .

JOURNAL OF CLINICAL MEDICINE, 2020, 9 (12)

[10] Pericardial adipose and aromatase: A new translational target for aging, obesity and arrhythmogenesis? [J].

Bernasochi, Gabriel B. ;

Boon, Wah Chin ;

Curl, Claire L. ;

Varma, Upasna ;

Pepe, Salvatore ;

Tare, Marianne ;

Parry, Laura J. ;

Dimitriadis, Evdokia ;

Harrap, Stephen B. ;

Nalliah, Chrishan J. ;

Kalman, Jonathan M. ;

Delbridge, Lea M. D. ;

Bell, James R. .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2017, 111 :96-101

← 1 2 3 4 5 6 7 8 9 10 →