Mutations in TP53 and DNA damage repair genes have a negative impact on the response to first-line systemic therapy in men with prostate cancer

被引：0

作者：

Nientiedt, C. ^{[1
,2
]}

Wuenschel, A. -K ^{[3
]}

Kaczorowski, A. ^{[3
]}

Endris, V ^{[4
]}

Zschaebitz, S. ^{[1
]}

Jaeger, D. ^{[1
]}

Hohenfellner, M. ^{[5
]}

Stenzinger, A.

Duensing, S. ^{[3
]}

机构：

[1] NCT Natl Ctr Tumorerkrankungen Heidelberg, Med Onkol, Heidelberg, Germany

[2] Klin Innere Med Hamatol Onkol & Stammzelltranspla, Freiburg, Germany

[3] Urol Clin, Mol Uroonkol, Heidelberg, Germany

[4] Pathol Inst, Allgemeine Pathol, Heidelberg, Germany

[5] Urol Clin, Heidelberg, Germany

来源：

ONCOLOGY RESEARCH AND TREATMENT | 2023年 / 46卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

V836

引用

页码：112 / 112

页数：1

共 50 条

[21] Germline DNA-repair Gene Mutations and Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Receiving First-line Abiraterone and Enzalutamide [J].

Antonarakis, Emmanuel S. ;

Lu, Changxue ;

Luber, Brandon ;

Liang, Chao ;

Wang, Hao ;

Chen, Yan ;

Silberstein, John L. ;

Piana, Danilo ;

Lai, Zhao ;

Chen, Yidong ;

Isaacs, William B. ;

Luo, Jun .

EUROPEAN UROLOGY, 2018, 74 (02) :218-225

[22] Germline mutations in the DNA damage response genes BRCA1, BRCA2, BARD1 and TP53 in patients with therapy related myeloid neoplasms [J].

Schulz, Eduard ;

Valentin, Angelika ;

Ulz, Peter ;

Beham-Schmid, Christine ;

Lind, Karin ;

Rupp, Verena ;

Lackner, Herwig ;

Woelfler, Albert ;

Zebisch, Armin ;

Olipitz, Werner ;

Geigl, Jochen ;

Berghold, Andrea ;

Speicher, Michael R. ;

Sill, Heinz .

JOURNAL OF MEDICAL GENETICS, 2012, 49 (07) :422-428

[23] Impact of DNA damage repair (DDR) mutations on treatment outcomes in men receiving conventional therapy for metastatic castration resistant prostate cancer (mCRPC) [J].

Carlson, Alex S. ;

Acevedo, Rigo ;

Lim, Daniel M. ;

Gulati, Roman ;

Yu, Evan Y. ;

Schweizer, Michael Thomas .

JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (06)

[24] DNA damage signaling in response to 5-fluorouracil in three colorectal cancer cell lines with different mismatch repair and TP53 status [J].

Adamsen, Birgitte L. ;

Kravik, Katherine L. ;

De Angelis, Paula M. .

INTERNATIONAL JOURNAL OF ONCOLOGY, 2011, 39 (03) :673-682

[25] Effect of germline DNA repair gene mutations on outcomes in men with metastatic castration-resistant prostate cancer receiving first-line abiraterone and enzalutamide. [J].

Antonarakis, Emmanuel S. ;

Lu, Changxue ;

Luber, Brandon ;

Wang, Hao ;

Chen, Yan ;

Silberstein, John ;

Piana, Danilo ;

Lai, Zhao ;

Chen, Yidong ;

Isaacs, William B. ;

Luo, Jun .

JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (06)

[26] Cribriform and Intraductal Carcinoma of the Prostate Frequently Harbor TP53, ATM and BRCA2 Gene Mutations Among Other Homologous Recombination DNA Repair Genes [J].

Jain, Ekta ;

Sharma, Shivani ;

Aggarwal, Aditi ;

Jain, Deepika ;

Malik, Vipra ;

Shinde, Sayali ;

Dixit, Mallika ;

Arora, Samriti ;

Singh, Hena ;

Varshney, Juhi ;

Lobo, Anandi ;

Amin, Mahul ;

Mohanty, Sambit .

LABORATORY INVESTIGATION, 2023, 103 (03) :S747-S748

[27] The possibility of mutations of RAS signaling genes and/or TP53 in combination as a negative prognostic impact on pathological stage I non-small cell lung cancer [J].

Honda, Takayuki ;

Seto, Katsutoshi ;

Endo, Satoshi ;

Takemoto, Akira ;

Tanimoto, Kousuke ;

Kobayashi, Masashi ;

Kitano, Masatake ;

Sakakibara, Rie ;

Mitsumura, Takahiro ;

Ishibashi, Hironori ;

Inazawa, Johji ;

Tanaka, Toshihiro ;

Miyazaki, Yasunari ;

Okubo, Kenichi .

CANCER MEDICINE, 2023, 12 (19) :19406-19413

[28] Impact of TP53 loss-of-function alterations on the response to PSMA radioligand therapy in metastatic castration-resistant prostate cancer patients [J].

Slootbeek, Peter H. J. ;

Luna-Velez, Maria Victoria ;

Prive, Bastiaan M. ;

van der Doelen, Maarten J. ;

Kloots, Iris S. H. ;

Naga, Samhita Pamidimarri ;

Onstenk, Hilde E. ;

Nagarajah, James ;

Westdorp, Harm ;

van Oort, Inge M. ;

Kroeze, Leonie I. ;

Schalken, Jack. A. ;

Bloemendal, Haiko J. ;

Mehra, Niven .

THERANOSTICS, 2024, 14 (12) :4555-4569

[29] Re: Germline DNA-Repair Gene Mutations and Outcomes in Men with Metastatic Castration-Resistant Prostate Cancer Receiving First-Line Abiraterone and Enzalutamide Editorial Comment [J].

Antonarakis, E. S. ;

Lu, C. ;

Luber, B. ;

Liang, C. ;

Wang, H. ;

Chen, Y. ;

Silberstein, J. L. ;

Piana, D. ;

Lai, Z. ;

Chen, Y. ;

Isaacs, W. B. ;

Luo, J. .

JOURNAL OF UROLOGY, 2018, 200 (05) :945-945

[30] Laboratory -Prostate cancer High prevalence of DNA damage repair gene defects and TP53 alterations in men with treatment-na??ve metastatic prostate cancer ?Results from a prospective pilot study using a 37 gene panel [J].

Nientiedt, Cathleen ;

Endris, Volker ;

Jenzer, Maximilian ;

Mansour, Josef ;

Sedehi, Nassim Tawanaie Pour ;

Pecqueux, Carine ;

Volckmar, Anna-Lena ;

Leichsenring, Jonas ;

Neumann, Olaf ;

Kirchner, Martina ;

Hoveida, Shirin ;

Lantwin, Philippa ;

Kaltenecker, Katrin ;

Dieffenbacher, Svenja ;

Gasch, Claudia ;

Hofer, Luisa ;

Franke, Desiree ;

Tosev, Georgi ;

Goertz, Magdalena ;

Schuetz, Viktoria ;

Radtke, Jan-Philipp ;

Nyarangi-Dix, Joanne ;

Hatiboglu, Gencay ;

Simpfendoerfer, Tobias ;

Schoenberg, Gita ;

Isaac, Sanjay ;

Teber, Dogu ;

Koerber, Stefan A. ;

Christofi, Georgia ;

Czink, Elena ;

Kreuter, Rebecca ;

Apostolidis, Leonidas ;

Kratochwil, Clemens ;

Giesel, Frederik ;

Haberkorn, Uwe ;

Debus, Juergen ;

Sueltmann, Holger ;

Zschaebitz, Stefanie ;

Jaeger, Dirk ;

Duensing, Anette ;

Schirmacher, Peter ;

Gruellich, Carsten ;

Hohenfellner, Markus ;

Stenzinger, Albrecht ;

Duensing, Stefan .

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2020, 38 (07)

← 1 2 3 4 5 →