Modulation of surfactant self-assembly in deep eutectic solvents and its relevance to drug delivery-A review

被引:30
作者
Basu, M. [1 ,2 ]
Hassan, Puthusserickal A. [1 ,2 ]
Shelar, Sandeep B. [1 ]
机构
[1] Bhabha Atom Res Ctr, Chem Div, Mumbai 400085, India
[2] Homi Bhabha Natl Inst, Training Sch Complex, Mumbai 400094, India
关键词
Deep eutectic solvents; Self-assembly; Surfactants; Structure and thermodynamics; Drug delivery; SODIUM DODECYL-SULFATE; CHOLINE CHLORIDE; MICELLAR GROWTH; CATIONIC SURFACTANTS; NEUTRON-SCATTERING; AQUEOUS-SOLUTIONS; IONIC-LIQUIDS; SDS MICELLES; TRANSITION; DESIGN;
D O I
10.1016/j.molliq.2023.121301
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A deep eutectic solvent (DES) is a low-melting liquid composed of a hydrogen bond acceptor (HBA) and hydrogen bond donor (HBD). It is prepared from readily available and inexpensive constituents that include many natural molecules like organic acids, alcohols, and sugars. Understanding the selfassembling behavior of amphiphiles in deep eutectic solvents will pave the way for new formulations in pharmaceutical and cosmetic applications. This review focuses on structural and thermodynamic aspects of DESs, the behavior of surfactants in different types of DESs, and applications of DESs and self-assembled structures in DESs in pharmaceutical technology. (c) 2023 Elsevier B.V. All rights reserved.
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页数:19
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