Synapses shape oligodendrocyte precursor cell development and predict myelination location

被引:0
作者
Li, Jiaxing [1 ]
Monk, Kelly R. [1 ]
机构
[1] Vollum Inst, Portland, OR 97239 USA
关键词
D O I
10.1038/s41593-023-01555-6
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Using in vivo imaging in zebrafish, we unveiled critical components (PSD-95, gephyrin and neuroligin-3) and dynamic properties of synapses between neurons and oligodendrocyte precursor cells (OPC). Furthermore, we showed that neuron-OPC synapses have a pivotal role in regulating OPC development and CNS myelination.
引用
收藏
页码:217 / 218
页数:2
相关论文
共 50 条
[41]   EPAC Negatively Regulates Myelination via Controlling Proliferation of Oligodendrocyte Precursor Cells [J].
Gao, Zhen-Zhen ;
Li, Ying-Cong ;
Shao, Chong-Yu ;
Xiao, Jian ;
Shen, Ying ;
Zhou, Liang .
NEUROSCIENCE BULLETIN, 2020, 36 (06) :639-648
[42]   Diversity of oligodendrocyte precursor cells with differential contribution to myelination revealed by in vivo imaging [J].
Hoche, T. ;
Czopka, T. .
GLIA, 2019, 67 :E751-E752
[43]   Oligodendrocyte development and the onset of myelination in the human fetal brain [J].
Jakovcevski, Igor ;
Filipovic, Radmila ;
Mo, Zhicheng ;
Rakic, Sonja ;
Zecevic, Nada .
FRONTIERS IN NEUROANATOMY, 2009, 3
[44]   Special Issue: Oligodendrocyte Development, Myelination and Related Diseases [J].
Rasband, Matt ;
Bansal, Rashmi ;
Macklin, Wendy ;
de Vellis, Jean .
JOURNAL OF NEUROSCIENCE RESEARCH, 2009, 87 (15) :3239-3240
[45]   Oligodendrocyte precursor cells engulf synapses during circuit remodeling in mice [J].
Auguste, Yohan S. S. ;
Ferro, Austin ;
Kahng, Jessica A. ;
Xavier, Andre M. ;
Dixon, Jessica R. ;
Vrudhula, Uma ;
Nichitiu, Anne-Sarah ;
Rosado, Daniele ;
Wee, Tse-Luen ;
Pedmale, Ullas, V ;
Cheadle, Lucas .
NATURE NEUROSCIENCE, 2022, 25 (10) :1273-+
[46]   EPAC Negatively Regulates Myelination via Controlling Proliferation of Oligodendrocyte Precursor Cells [J].
Zhen-Zhen Gao ;
Ying-Cong Li ;
Chong-Yu Shao ;
Jian Xiao ;
Ying Shen ;
Liang Zhou .
Neuroscience Bulletin, 2020, 36 :639-648
[47]   Icaritin Promotes Myelination by Simultaneously Enhancing the Proliferation and Differentiation of Oligodendrocyte Precursor Cells [J].
Yang, Feifei ;
Wen, Han ;
Ma, Siqi ;
Chang, Qi ;
Pan, Ruile ;
Liu, Xinmin ;
Liao, Yonghong .
MOLECULES, 2023, 28 (15)
[48]   mTOR signaling in oligodendrocyte progenitor cell differentiation and myelination [J].
Wood, T. ;
McLane, L. ;
Wahl, S. ;
Ornelas, I. ;
Saliu, A. .
GLIA, 2015, 63 :E27-E28
[49]   Evolution of the oligodendrocyte cell type and adaptive myelination phenotype [J].
Hines, J. H. .
GLIA, 2021, 69 :E35-E36
[50]   Evolutionary Origins of the Oligodendrocyte Cell Type and Adaptive Myelination [J].
Hines, Jacob H. .
FRONTIERS IN NEUROSCIENCE, 2021, 15