NANOPARTICLE-MEDIATED DELIVERY OF INSULIN-LIKE GROWTH FACTOR 1 TO THE PLACENTA IN THE NON-HUMAN PRIMATE IS SAFE AND REGULATES PLACENTAL SIGNALING

被引：0
|
作者：
Wilson, Rebecca L. [1 ,2 ]
Schmidt, Jenna Kropp [3 ]
Ren, Emily [3 ]
Keding, Logan T. [3 ]
Shaw, Sarah A. [3 ]
Heselton, Avery R. [3 ]
Schotzko, Michele L. [3 ]
Antony, Kathleen M. [4 ]
Fitz, Casey [3 ]
Simmons, Heather A. [3 ]
Basu, Puja [3 ]
Golos, Thaddeus G. [3 ,4 ,5 ]
Jones, Helen N. [1 ,2 ]
机构：
[1] Univ Florida, Dept Physiol & Aging, Coll Med, Gainesville, FL USA
[2] Univ Florida, Coll Med, Ctr Res Perinatal Outcomes, Gainesville, FL USA
[3] Univ Wisconsin Madison, Wisconsin Natl Primate Res Ctr, Madison, WI USA
[4] Univ Wisconsin Madison, Dept Obstet & Gynecol, Madison, WI USA
[5] Univ Wisconsin Madison, Dept Comparat Biosci, Madison, WI USA
来源：
PLACENTA | 2023年 / 140卷
关键词：
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
P1.75
引用
收藏
页码：E56 / E56
页数：1
相关论文
共 50 条
  • [1] INSULIN-LIKE GROWTH FACTOR-1 OVER-EXPRESSION FOLLOWING NANOPARTICLE-MEDIATED TRANSGENE DELIVERY INTO HUMAN PLACENTAL SYNCYTIUM
    Owens, Kathryn
    Jones, Helen
    PLACENTA, 2016, 45 : 98 - 98
  • [2] Nanoparticle-Mediated Gene Transfer in Non-Human Primate Eyes
    Han, Zongchao
    Koirala, Adarsha
    Wolf, Roman F.
    Makkia, Rasha
    Conley, Shannon M.
    Carey, David W.
    Shaw, Ryan A.
    Guo, Junjing
    Cooper, Mark J.
    Naash, Muna I.
    MOLECULAR THERAPY, 2014, 22 : S49 - S49
  • [3] Nanoparticle mediated increased insulin-like growth factor 1 expression enhances human placenta syncytium function
    Wilson, Rebecca L.
    Owens, Kathryn
    Sumser, Emily K.
    Fry, Matthew V.
    Stephens, Kendal K.
    Chuecos, Marcel
    Carrillo, Maira
    Schlabritz-Loutsevitch, Natalia
    Jones, Helen N.
    PLACENTA, 2020, 93 : 1 - 7
  • [4] Nanoparticle-mediated transgene expression of insulin-like growth factor 1 in the growth restricted guinea pig placenta increases placenta nutrient transporter expression and fetal glucose concentrations
    Wilson, Rebecca L.
    Lampe, Kristin
    Gupta, Mukesh K.
    Duvall, Craig L.
    Jones, Helen N.
    MOLECULAR REPRODUCTION AND DEVELOPMENT, 2022, 89 (11) : 540 - 553
  • [5] Nanoparticle-Mediated Transgene Expression of Insulin-like Growth Factor 1 in the Guinea Pig Placenta Reduces Angiogenic Factor Transcription but Enhances Glucose Transporter Expression.
    Wilson, Rebecca L.
    Stephens, Kendal
    Lampe, Kristin
    Jones, Helen
    REPRODUCTIVE SCIENCES, 2020, 27 (SUPPL 1) : 70A - 70A
  • [6] Insulin-Like Growth Factor 1 Regulates Lipid Accumulation in Macrophages - A Potential Mechanism for Insulin-Like Growth Factor 1 Mediated Atheroprotection
    Higashi, Yusuke
    Shai, Shaw-Yung
    Sukhanov, Sergiy
    Kim, Catherine
    Snarski, Patricia
    Delafontaine, Patrice
    CIRCULATION, 2013, 128 (22)
  • [7] INSULIN-LIKE GROWTH FACTOR 1 REGULATES LIPID ACCUMULATION IN MACROPHAGES - A POTENTIAL MECHANISM FOR INSULIN-LIKE GROWTH FACTOR 1 MEDIATED ATHEROPROTECTION
    Higashi, Y.
    Shai, S.
    Sukhanov, S.
    Kim, C.
    Snarski, P.
    Delafontaine, P.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2014, 62 (02) : 523 - 523
  • [8] NANOPARTICLE-MEDIATED PLACENTAL GROWTH FACTOR DELIVERY AS A NOVEL THERAPY FOR ACUTE MYOCARDIAL INFARCTION
    Binsalamah, Z.
    Paul, A.
    Khan, A.
    Prakash, S.
    Shum-Tim, D.
    CANADIAN JOURNAL OF CARDIOLOGY, 2011, 27 (05) : S320 - S320
  • [9] Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis - Studies in a non-human primate model of naturally occurring disease
    Loeser, RF
    Shanker, G
    Carlson, CS
    Gardin, JF
    Shelton, BJ
    Sonntag, WE
    ARTHRITIS AND RHEUMATISM, 2000, 43 (09): : 2110 - 2120
  • [10] Regulation of Insulin-Like Growth Factor 1 (IGF1) Signaling in the Guinea Pig Placenta Following Nanoparticle Delivery of Human IGF1 Is Dependent on Fetal Phenotype.
    Wilson, Rebecca L.
    Stephens, Kendal
    Lampe, Kristin
    Jones, Helen
    REPRODUCTIVE SCIENCES, 2021, 28 (SUPPL 1) : 178A - 178A
12345