Alopecia associated with dimethyl fumarate treatment for multiple sclerosis

被引：1

作者：

Abicic, Ana ^{[1
]}

Adamec, Ivan ^{[2
,3
]}

Habek, Mario ^{[2
,3
]}

机构：

[1] Gen Hosp Zabok, Zabok, Croatia

[2] Univ Hosp Ctr Zagreb, Referral Ctr Auton Nervous Syst Disorders, Dept Neurol, Kispaticeva 12, Zagreb 10000, Croatia

[3] Univ Zagreb, Sch Med, Zagreb, Croatia

来源：

WIENER MEDIZINISCHE WOCHENSCHRIFT | 2023年 / 173卷 / 11-12期

关键词：

Dimethyl fumarate; Alopecia; Multiple sclerosis; Disease-modifying therapy; Adverse events;

D O I：

10.1007/s10354-023-01007-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

After 2 weeks of treatment, a woman with multiple sclerosis treated with dimethyl fumarate developed alopecia. Considering the adverse events, the therapy was discontinued, leading to alopecia regression during the next 3 months. Although the precise mechanism has not been completely elucidated, glutathione depletion or downregulation of aerobic glycolysis are considered to be potential reasons for hair loss induction. The incidence and mechanism of this uncommon adverse reaction to dimethyl fumarate should be further investigated.

引用

页码：287 / 289

页数：3

共 9 条

[1] Teriflunomide in Patients with Relapsing-Remitting Forms of Multiple Sclerosis [J].