A Systematic and Universal Artificial Intelligence Screening Method for Oropharyngeal Dysphagia: Improving Diagnosis Through Risk Management

被引:18
作者
Martin-Martinez, Alberto [1 ,4 ]
Miro, Jaume [1 ,2 ]
Amado, Cristina [1 ]
Ruz, Francisco [3 ]
Ruiz, Antonio [3 ]
Ortega, Omar [1 ,4 ]
Clave, Pere [1 ,4 ]
机构
[1] Univ Autonoma Barcelona, Hosp Mataro, Gastrointestinal Physiol Lab, CIBERehd CSdM UAB, Carretera Cirera 230, Mataro 08304, Spain
[2] Fundacio Salut Consorci Sanitari Maresme, Mataro, Spain
[3] Consorci Sanitari Maresme, IT Dept, Mataro, Spain
[4] Ctr Invest Biomed Red Enfermedades Hepat & Digest, Barcelona, Spain
关键词
Dysphagia; Swallowing disorders; Machine learning; Aging; Screening methods; Diagnostics; EATING ASSESSMENT-TOOL; VISCOSITY SWALLOW TEST; HEALTH-CARE; ASPIRATION; DISEASE; MALNUTRITION; DISORDERS; PNEUMONIA; OUTCOMES;
D O I
10.1007/s00455-022-10547-w
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Oropharyngeal dysphagia (OD) is underdiagnosed and current screening is costly. We aimed: (a) to develop an expert system (ES) based on machine learning that calculates the risk of OD from the electronic health records (EHR) of all hospitalized older patients during admission, and (b) to implement the ES in a general hospital. In an observational, retrospective study, EHR and swallowing assessment using the volume-viscosity swallow test for OD were captured over 24 months in patients > 70 yr admitted to Mataro Hospital. We studied the predictive power for OD of 25,000 variables. ES was obtained using feature selection, the final prediction model was built with non-linear methods (Random Forest). The database included 2809 older patients (mean age 82.47 +/- 9.33 yr), severely dependent (Barthel Index 47.68 +/- 31.90), with multiple readmissions (4.06 +/- 7.52); 75.76% had OD. The psychometrics of the ES built with a non-linear model were: Area under the ROC Curve of 0.840; sensitivity 0.940; specificity, 0.416; Positive Predictive Value 0.834; Negative Predictive Value 0.690; positive likelihood ratio (LH), 1.61 and negative LH, 0.146. The ES screens in 6 s all patients admitted to a 419-bed hospital, identifies patients at greater risk of OD, and shows the risk for OD in the clinician's workstation. It is currently in use at our institution. Our ES provides accurate, systematic and universal screening for OD in real time during hospital admission of older patients, allowing the most appropriate diagnostic and therapeutic strategies to be selected for each patient.
引用
收藏
页码:1224 / 1237
页数:14
相关论文
共 70 条
[1]   Oropharyngeal Dysphagia in the Elderly: Evaluation and Prevalence [J].
Abu-Ghanem, Sara ;
Chen, Sophia ;
Amin, Milan R. .
CURRENT OTORHINOLARYNGOLOGY REPORTS, 2020, 8 (01) :34-42
[2]   Aspiration pneumonia [J].
Almirall, Jordi ;
Cabre, Mateu ;
Clave, Pere .
MEDICINA CLINICA, 2007, 129 (11) :424-432
[3]   Oropharyngeal dysphagia is a risk factor for community-acquired pneumonia in the elderly [J].
Almirall, Jordi ;
Rofes, Laia ;
Serra-Prat, Mateu ;
Icart, Roser ;
Palomera, Elisabet ;
Arreola, Viridiana ;
Clave, Pere .
EUROPEAN RESPIRATORY JOURNAL, 2013, 41 (04) :923-928
[4]   Natural History of Swallow Function during the Three-Month Period after Stroke [J].
Arreola, Viridiana ;
Vilardell, Natalia ;
Ortega, Omar ;
Rofes, Laia ;
Muriana, Desiree ;
Palomeras, Ernest ;
Alvarez-Berdugo, Daniel ;
Clave, Pere .
GERIATRICS, 2019, 4 (03)
[5]   Impact of oropharyngeal dysphagia on healthcare cost and length of stay in hospital: a systematic review [J].
Attrill, Stacie ;
White, Sarahlouise ;
Murray, Joanne ;
Hammond, Sue ;
Doeltgen, Sebastian .
BMC HEALTH SERVICES RESEARCH, 2018, 18
[6]   European Society for Swallowing Disorders European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome [J].
Baijens, Laura W. J. ;
Clave, Pere ;
Cras, Patrick ;
Ekberg, Olle ;
Forster, Alexandre ;
Kolb, Gerald F. ;
Leners, Jean-Claude ;
Masiero, Stefano ;
Mateos-Nozal, Jesus ;
Ortega, Omar ;
Smithard, David G. ;
Speyer, Renee ;
Walshe, Margaret .
CLINICAL INTERVENTIONS IN AGING, 2016, 11 :1403-1428
[7]  
Barczi S R, 2000, Semin Speech Lang, V21, P347, DOI 10.1055/s-2000-8387
[8]   Big Data In Health Care: Using Analytics To Identify And Manage High-Risk And High-Cost Patients [J].
Bates, David W. ;
Saria, Suchi ;
Ohno-Machado, Lucila ;
Shah, Anand ;
Escobar, Gabriel .
HEALTH AFFAIRS, 2014, 33 (07) :1123-1131
[9]   Validity and Reliability of the Eating Assessment Tool (EAT-10) [J].
Belafsky, Peter C. ;
Mouadeb, Debbie A. ;
Rees, Catherine J. ;
Pryor, Jan C. ;
Postma, Gregory N. ;
Allen, Jacqueline ;
Leonard, Rebecca J. .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2008, 117 (12) :919-924
[10]   Random forests [J].
Breiman, L .
MACHINE LEARNING, 2001, 45 (01) :5-32