Iodine Mediated Oxidative Cross-Coupling of Benzo[d]Imidazo[2,1-b]Thiazoles with Ethylbenzene: An Unprecedented Approach of C3-Dicarbonylation

被引：1

作者：

Jinkala, Rajesh ^{[1
,2
]}

Tadiparthi, Krishnaji ^{[3
]}

Raghunadh, Akula ^{[1
]}

Kumar, K. B. Shiva ^{[1
]}

Venkateshwarlu, Rapolu ^{[1
]}

Siddaiah, Vidavalur ^{[2
]}

Ramamohan, Hindupur ^{[1
]}

机构：

[1] Dr Reddys Labs Ltd, Custom Pharmaceut Serv, Technol Dev Ctr, Hyderabad, India

[2] Andhra Univ, Dept Organ Chem & FDW, Visakhapatnam, Andhra Pradesh, India

[3] CHRIST Deemed Univ, Dept Chem, Hosur Rd, Bangalore 560026, Karnataka, India

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2023年 / 43卷 / 05期

关键词：

Benzo[d]imidazo[2; 1-b]thiazoles; dicarbonylation; iodine; ONE-POT SYNTHESIS; BOND-CLEAVAGE; IN-VITRO; KETONES; 1,2-DIKETONES; ROUTE; STRATEGY; INDOLES; ALKYNES; ACIDS;

D O I：

10.1080/10406638.2022.2083198

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A versatile approach of iodine mediated C3-dicarbonylation of benzo[d]imidazo[2,1-b]thiazoles (IBTs) with ethylbenzene has been reported. The reaction conditions were optimized by screening in various solvents, catalysts, and oxidants. The reaction is compatible with various substrates and was successfully demonstrated to offer moderate to good yields.

引用

页码：4045 / 4054

页数：10

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