Research Progress of Multi-signal Fluorescent Probes for Simultaneous Detection of Biothiols

被引：1
作者：
Liu, Tiantian [1 ]
Zhang, Hongpeng [1 ]
Jiao, Xiaomeng [1 ]
Bai, Yinjuan [1 ]
机构：
[1] Northwest Univ, Coll Chem Mat Sci, Key Lab Synthet & Natl Funct Mol Chem, Minist Educ, Xian 710127, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 43卷 / 06期
基金：
中国国家自然科学基金;
关键词：
biothiol; fluorescent probe; simultaneous detection; multi-signal; LIVING CELLS; SIMULTANEOUS DISCRIMINATION; SELECTIVE DETECTION; GLUTATHIONE; GSH; HOMOCYSTEINE; CYSTEINE; CYS/HCY; CYS; CYSTEINE/HOMOCYSTEINE;
D O I：
10.6023/cjoc202210034
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
There is a close relationship between different biothiols. The changes of one biothiol level in a specific cell metabolism process may be related to the variation of another biothiol, and many diseases are the result of the combination of two or more biothiols. The simultaneous detection of divers biological thiols by fluorescence method is of particular importance for biological research and disease diagnosis. In recent years, breakthrough results have been achieved in this field. The research progress of multi-signal fluorescent probes in the field of simultaneous detection of biothiols is reviewed. According to the objects detected by the probes, the fluorescent probes are systemically classified and discussed, and the corresponding design concept, optical properties, detection mechanism, recognition performance and biological applications are summarized. At the same time, the future development and application in this field are proposed.
引用
收藏
页码：2081 / 2095
页数：15
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