Mechanical characterization of osteoporosis based on x-ray induced acoustic computed tomography

被引:1
|
作者
Hu, Yang [1 ]
Zhang, Xingchao [1 ]
Su, Ningning [1 ]
Shi, Xiaohan [2 ]
Chen, Jiahui [1 ]
Wu, Hui [1 ]
Liu, Guoqing [3 ]
Li, Liming [1 ]
Bai, Caixun [1 ]
Xiu, Junshan [1 ]
Zhao, Yue [1 ]
机构
[1] Shandong Univ Technol, Sch Phys & Optoelect Engn, Zibo 255049, Peoples R China
[2] Shandong Univ Technol, Sch Mech Engn, Zibo 255049, Peoples R China
[3] Binzhou Polytech, Binzhou 256600, Peoples R China
基金
中国国家自然科学基金;
关键词
BONE; MICROSCOPY; SIMULATION;
D O I
10.1063/5.0160580
中图分类号
O59 [应用物理学];
学科分类号
摘要
X-ray induced acoustic computed tomography (XACT) utilized the ultrasound generated by the thermoelastic effect to reconstruct the x-ray absorption distribution of tissues. In this Letter, we propose a method for mechanical characterization of osteoporosis based on an XACT technique. The theoretical and simulation studies were performed on the influence of elasticity effect on x-ray induced acoustic (XA) generation. The images of normal and osteoporotic bones reconstructed by the simulated XACT were found to be in good agreement with micro-CT. Furthermore, through XA signal analysis, the rise time of tissue displacement can be obtained to characterize the elasticity of bone tissues. Experimental results demonstrated that this method can provide structural and mechanical information of bone tissues, which has future potentials for assessment of bone in osteoporosis.
引用
收藏
页数:5
相关论文
共 50 条
  • [41] Dynamic X-ray computed tomography
    Bonnet, S
    Koenig, A
    Roux, S
    Hugonnard, P
    Guillemaud, R
    Grangeat, P
    PROCEEDINGS OF THE IEEE, 2003, 91 (10) : 1574 - 1587
  • [42] Industrial computed X-ray tomography
    Luthi, T
    Flisch, A
    Wyss, P
    INSIGHT, 1998, 40 (03) : 196 - 197
  • [43] Design for X-Ray Computed Tomography
    Moroni, Giovanni
    Petro, Stefano
    29TH CIRP DESIGN CONFERENCE 2019, 2019, 84 : 173 - 178
  • [44] Microstructures characterization of TATB based granules by high resolution X-ray computed tomography
    Zhang, W.-B. (weibinzhang1@163.com), 1600, Editorial Board of Chinese Journal of Energetic Materials, P.O. Box 919-310, Mianyang, 621900, China (21):
  • [45] Dose in x-ray computed tomography
    Kalender, Willi A.
    PHYSICS IN MEDICINE AND BIOLOGY, 2014, 59 (03): : R129 - R150
  • [46] A multifunctional mechanical testing stage for micro x-ray computed tomography
    Ruf, Matthias
    Lee, Dongwon
    Steeb, Holger
    REVIEW OF SCIENTIFIC INSTRUMENTS, 2023, 94 (08):
  • [47] X-ray computed tomography of the heart
    Wijesekera, Nevin T.
    Duncan, Mark K.
    Padley, Simon P. G.
    BRITISH MEDICAL BULLETIN, 2010, 93 (01) : 49 - 67
  • [48] Induced polarization of rocks containing pyrite: Interpretation based on X-ray computed tomography
    Gurin, Grigory
    Ilyin, Yuri
    Nilov, Sergey
    Ivanov, Danil
    Kozlov, Evgeny
    Titov, Konstantin
    JOURNAL OF APPLIED GEOPHYSICS, 2018, 154 : 50 - 63
  • [49] Towards quantitative in vivo dosimetry using x-ray acoustic computed tomography
    Sun, Leshan
    Gonzalez, Gilberto
    Pandey, Prabodh Kumar
    Wang, Siqi
    Kim, Kaitlyn
    Limoli, Charles
    Chen, Yong
    Xiang, Liangzhong
    MEDICAL PHYSICS, 2023, 50 (11) : 6894 - 6907
  • [50] Experimental evaluation of x-ray acoustic computed tomography for radiotherapy dosimetry applications
    Hickling, Susannah
    Lei, Hao
    Hobson, Maritza
    Leger, Pierre
    Wang, Xueding
    El Naqa, Issam
    MEDICAL PHYSICS, 2017, 44 (02) : 608 - 617