Mechanical characterization of osteoporosis based on x-ray induced acoustic computed tomography

被引:1
|
作者
Hu, Yang [1 ]
Zhang, Xingchao [1 ]
Su, Ningning [1 ]
Shi, Xiaohan [2 ]
Chen, Jiahui [1 ]
Wu, Hui [1 ]
Liu, Guoqing [3 ]
Li, Liming [1 ]
Bai, Caixun [1 ]
Xiu, Junshan [1 ]
Zhao, Yue [1 ]
机构
[1] Shandong Univ Technol, Sch Phys & Optoelect Engn, Zibo 255049, Peoples R China
[2] Shandong Univ Technol, Sch Mech Engn, Zibo 255049, Peoples R China
[3] Binzhou Polytech, Binzhou 256600, Peoples R China
基金
中国国家自然科学基金;
关键词
BONE; MICROSCOPY; SIMULATION;
D O I
10.1063/5.0160580
中图分类号
O59 [应用物理学];
学科分类号
摘要
X-ray induced acoustic computed tomography (XACT) utilized the ultrasound generated by the thermoelastic effect to reconstruct the x-ray absorption distribution of tissues. In this Letter, we propose a method for mechanical characterization of osteoporosis based on an XACT technique. The theoretical and simulation studies were performed on the influence of elasticity effect on x-ray induced acoustic (XA) generation. The images of normal and osteoporotic bones reconstructed by the simulated XACT were found to be in good agreement with micro-CT. Furthermore, through XA signal analysis, the rise time of tissue displacement can be obtained to characterize the elasticity of bone tissues. Experimental results demonstrated that this method can provide structural and mechanical information of bone tissues, which has future potentials for assessment of bone in osteoporosis.
引用
收藏
页数:5
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