Previous SARS-CoV-2 Infection Is Not Associated With Increased Celiac Disease Autoimmunity in Children and Adolescents

被引:1
作者
Corrado, Michelle M. [1 ]
Jia, Xiaofan [2 ]
Rasmussen, Cristy Geno [2 ]
Pyle, Laura [2 ]
Yu, Liping [2 ]
Liu, Edwin [1 ]
Stahl, Marisa [1 ]
Rewers, Marian J. [2 ]
机构
[1] Univ Colorado, Digest Hlth Inst, Childrens Hosp Colorado, Aurora, CO 80045 USA
[2] Univ Colorado, Barbara Davis Ctr Diabet, Aurora, CO USA
关键词
celiac disease; SARS-CoV-2; COVID-19; screening;
D O I
10.14309/ajg.0000000000002317
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
INTRODUCTION:Recent reports suggest severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections may increase the risk of celiac disease autoimmunity. This study aims to evaluate potential associations between coronavirus disease 2019 infection and tissue transglutaminase autoantibodies (TGA) immunoglobulin A.METHODS:From 2020 to 2021, cross-sectional screening for SARS-CoV-2 antibodies and TGA was offered to 4,717 children in Colorado through the Autoimmunity Screening for Kids study. Multivariable logistic regression assessed association between previous SARS-CoV-2 infection and TGA positivity.RESULTS:Previous SARS-CoV-2 infection was not associated with TGA positivity (odds ratio 1.02, 95% confidence interval 0.63-1.59; P = 0.95).DISCUSSION:In this large-scale analysis, previous SARS-CoV-2 infection was not associated with celiac disease autoimmunity in Colorado children.
引用
收藏
页码:1698 / 1700
页数:3
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