A Case Report of Mediastinal Teratoma in a Pediatric Patient With Nephrotic Syndrome: Paraneoplastic Syndrome or Incidental Finding?

被引:1
作者
Alva, Heather L. [1 ,5 ]
Ahn, Haejun [2 ]
Zhao, Xixi [3 ]
Obeidat, Mohammad [4 ]
Charu, Vivek [4 ]
Crane, Jacquelyn N. [1 ]
Marsenic, Olivera [2 ]
机构
[1] Stanford Univ, Sch Med, Dept Pediat Oncol Stem Cell Transplantat & Regener, Div Pediat Hematol, Palo Alto, CA USA
[2] Stanford Univ, Sch Med, Dept Pediat, Div Pediat Nehrol, Palo Alto, CA USA
[3] Stanford Univ, Sch Med, Dept Med & Pediat, Div Pediat Nephrol,Div Nephrol, Palo Alto, CA USA
[4] Stanford Univ, Sch Med, Dept Pathol, Palo Alto, CA USA
[5] Stanford Univ, Sch Med, Dept Pediat Stem Cell Transplant & Regenerat Med, Div Hematol Oncol, 1000 Welch Rd,Suite 300,MC 5798, Palo Alto, CA 94304 USA
基金
美国国家卫生研究院;
关键词
mature teratoma; nephrotic syndrome; pediatrics; minimal change disease; mediastinal mass; OVARIAN TUMOR; GLOMERULOPATHIES; GIRL;
D O I
10.1097/MPH.0000000000002684
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A 12-year-old female presented with weight gain, edema, and shortness of breath. Laboratory and urine studies confirmed nephrotic syndrome and presence of a mediastinal mass, identified as a mature teratoma after resection. Nephrotic syndrome persisted despite resection and renal biopsy confirmed minimal change disease, which ultimately responded to steroid treatment. She had two relapses of nephrotic syndrome after vaccination administration, both of which occurred within eight months of tumor resection and were responsive to steroids. Autoimmune and infectious workup for other causes of nephrotic syndrome was negative. This is the first reported case of nephrotic syndrome associated with mediastinal teratoma.
引用
收藏
页码:E631 / E634
页数:4
相关论文
共 14 条
[1]   Paraneoplastic glomerular diseases and malignancies [J].
Bacchetta, Justine ;
Juillard, Laurent ;
Cochat, Pierre ;
Droz, Jean-Pierre .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2009, 70 (01) :39-58
[2]   MEMBRANOUS NEPHROPATHY ASSOCIATED WITH OVARIAN TUMOR IN A YOUNG GIRL - RECOVERY AFTER REMOVAL [J].
BEAUVAIS, P ;
VAUDOUR, G ;
GIBOD, LB ;
LEVY, M .
EUROPEAN JOURNAL OF PEDIATRICS, 1989, 148 (07) :624-625
[3]   Ovarian tumor and glomerulopathies: case report and review of the literature [J].
Benabdellah, Nawal ;
Izzedine, Hassan ;
Bentata, Yassamine ;
Haddiya, Intissar .
PAN AFRICAN MEDICAL JOURNAL, 2019, 34
[4]   Mediastinal Germ Cell Tumors in Pediatric Patients: A Report From the Italian Association of Pediatric Hematology and Oncology [J].
De Pasquale, Maria Debora ;
Crocoli, Alessandro ;
Conte, Massimo ;
Indolfi, Paolo ;
D'Angelo, Paolo ;
Boldrini, Renata ;
Terenziani, Monica ;
Inserra, Alessandro .
PEDIATRIC BLOOD & CANCER, 2016, 63 (05) :808-812
[5]  
Gobel U, 1998, MED PEDIATR ONCOL, V31, P8
[6]  
Jeroudi Abdallah, 2013, Saudi J Kidney Dis Transpl, V24, P777
[7]   Paraneoplastic Glomerular Diseases [J].
Jeyabalan, Anushya ;
Trivedi, Mayuri .
ADVANCES IN CHRONIC KIDNEY DISEASE, 2022, 29 (02) :116-+
[8]   Unspecific Increase of Tumor Markers in a Girl with Nephrotic Syndrome and Ovarian Teratoma [J].
Kilis-Pstrusinska, Katarzyna ;
Szajerka, Urszula ;
Zwolinska, Danuta .
RENAL FAILURE, 2013, 35 (05) :654-656
[9]   Ovarian teratoma in children: a plea for collaborative clinical study [J].
Luczak, Justyna ;
Baglaj, Maciej .
JOURNAL OF OVARIAN RESEARCH, 2018, 11
[10]   ROLE OF RESPIRATORY VIRUSES IN EXACERBATIONS OF PRIMARY NEPHROTIC SYNDROME [J].
MACDONALD, NE ;
WOLFISH, N ;
MCLAINE, P ;
PHIPPS, P ;
ROSSIER, E .
JOURNAL OF PEDIATRICS, 1986, 108 (03) :378-382