A Case Report of Mediastinal Teratoma in a Pediatric Patient With Nephrotic Syndrome: Paraneoplastic Syndrome or Incidental Finding?

被引:0
|
作者
Alva, Heather L. [1 ,5 ]
Ahn, Haejun [2 ]
Zhao, Xixi [3 ]
Obeidat, Mohammad [4 ]
Charu, Vivek [4 ]
Crane, Jacquelyn N. [1 ]
Marsenic, Olivera [2 ]
机构
[1] Stanford Univ, Sch Med, Dept Pediat Oncol Stem Cell Transplantat & Regener, Div Pediat Hematol, Palo Alto, CA USA
[2] Stanford Univ, Sch Med, Dept Pediat, Div Pediat Nehrol, Palo Alto, CA USA
[3] Stanford Univ, Sch Med, Dept Med & Pediat, Div Pediat Nephrol,Div Nephrol, Palo Alto, CA USA
[4] Stanford Univ, Sch Med, Dept Pathol, Palo Alto, CA USA
[5] Stanford Univ, Sch Med, Dept Pediat Stem Cell Transplant & Regenerat Med, Div Hematol Oncol, 1000 Welch Rd,Suite 300,MC 5798, Palo Alto, CA 94304 USA
基金
美国国家卫生研究院;
关键词
mature teratoma; nephrotic syndrome; pediatrics; minimal change disease; mediastinal mass; OVARIAN TUMOR; GLOMERULOPATHIES; GIRL;
D O I
10.1097/MPH.0000000000002684
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A 12-year-old female presented with weight gain, edema, and shortness of breath. Laboratory and urine studies confirmed nephrotic syndrome and presence of a mediastinal mass, identified as a mature teratoma after resection. Nephrotic syndrome persisted despite resection and renal biopsy confirmed minimal change disease, which ultimately responded to steroid treatment. She had two relapses of nephrotic syndrome after vaccination administration, both of which occurred within eight months of tumor resection and were responsive to steroids. Autoimmune and infectious workup for other causes of nephrotic syndrome was negative. This is the first reported case of nephrotic syndrome associated with mediastinal teratoma.
引用
收藏
页码:E631 / E634
页数:4
相关论文
共 50 条
  • [1] Lung cancer with nephrotic syndrome as a paraneoplastic syndrome: A case report
    Yu, Xuesong
    Fan, Zhiming
    Chen, Wei
    Wang, Zhe
    MOLECULAR AND CLINICAL ONCOLOGY, 2020, 13 (06) : 1 - 4
  • [2] Gastrointestinal stromal tumor with nephrotic syndrome as a paraneoplastic syndrome: A case report
    Takane K.
    Midorikawa Y.
    Yamazaki S.
    Kajiwara T.
    Yoshida N.
    Kusumi Y.
    Takayama T.
    Journal of Medical Case Reports, 8 (1)
  • [3] A case of paraneoplastic nephrotic syndrome in a patient with ovarian carcinoma
    Kim, YT
    Rha, SY
    Shim, CY
    Sohn, JH
    Kim, C
    Yu, NC
    Chung, HC
    Kim, JH
    Han, DS
    Kim, BS
    Roh, JK
    YONSEI MEDICAL JOURNAL, 2003, 44 (03) : 539 - 543
  • [4] Case Report: Nephrotic syndrome as the primary manifestation of Alport syndrome in a Chinese pediatric patient
    Song, Yue
    Li, Yifei
    Lu, Liqun
    Yang, Changqiang
    Lu, Jing
    FRONTIERS IN PEDIATRICS, 2025, 12
  • [5] Kimura disease of buccal region in a pediatric patient with nephrotic syndrome A case report
    Lee, Dong Hoon
    Kim, Ga-Eon
    Yang, Eunmi
    Yoon, Tae Mi
    Lee, Joon Kyoo
    Lim, Sang Chul
    MEDICINE, 2017, 96 (48)
  • [6] Recurrent paraneoplastic nephrotic syndrome; insights from a Lynch syndrome patient with multiple malignancies
    de Jong, Myrthe A.
    Slingerland, Marije
    Hawinkels, Lukas J. A. C.
    Nielsen, Maartje
    Crobach, Augustinus S. L. P.
    de Jonge-Muller, Eveline S. M.
    Rabelink, Antonius J.
    Langers, Alexandra M. J.
    FAMILIAL CANCER, 2025, 24 (01)
  • [9] Nephrotic syndrome and microhematuria in a patient with nutcracker syndrome: Report of a case and review of the literature
    Schoeffel, N.
    Liehr, R. -M.
    Buenger, C.
    Krueger, K.
    Rubin, D.
    INTERNIST, 2018, 59 (06): : 608 - 614
  • [10] Nephrotic syndrome as paraneoplastic syndrome of Hodgkin Disease
    B. Utsch
    G. Fleischhack
    C. Hasan
    U. Bode
    European Journal of Pediatrics, 1999, 158 : 768 - 768