A comprehensive review on transdermal patches as an efficient approach for the delivery of drug

被引:5
|
作者
Ashfaq, Ansa [1 ]
Riaz, Tehseen [1 ]
Waqar, Muhammad Ahsan [2 ]
Zaman, Muhammad [1 ]
Majeed, Imtiaz [1 ]
机构
[1] Univ Cent Punjab, Fac Pharmaceut Sci, Lahore, Pakistan
[2] Lahore Univ Biol & Appl Sci, Fac Pharmaceut Sci, Dept Pharmaceut, Lahore, Pakistan
来源
POLYMER-PLASTICS TECHNOLOGY AND MATERIALS | 2024年 / 63卷 / 08期
关键词
Characterization; drug hydrolysis; skin irritation study; transdermal drug delivery system; transdermal patch; IN-VITRO EVALUATION; CHEMICAL PENETRATION ENHANCERS; PRESSURE-SENSITIVE ADHESIVES; MICRONEEDLE PATCH; PHARMACOKINETIC PROPERTIES; ALZHEIMERS-DISEASE; NITRIC-OXIDE; SYSTEM; FORMULATION; ESTRADIOL;
D O I
10.1080/25740881.2024.2317408
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
In past years, various studies have considered transdermal drug delivery system for improving patient compliance. One approach to deliver drug via transdermal route is transdermal patch. These patches include single-layer drug in adhesive patches and micro reservoir transdermal patch & matrix system. Acrylic-acid, hydroxypropyl methylcellulose (HPMC) and polyethylene glycol are commonly used polymers for manufacturing of transdermal patches. Characterization of patches includes patch thickness, weight uniformity, irritation studies, in-vitro drug release and permeation studies. This review summarizes various polymers, types of transdermal patches and evaluation of transdermal patches based on up-to-date data extracted from reputed journals and official websites.
引用
收藏
页码:1045 / 1069
页数:25
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