Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment

被引:1
作者
Gasior, Gabriela [1 ]
Grodzicka, Marlena [1 ]
Jedrzejewski, Tomasz [2 ]
Wisniewski, Marek [1 ]
Radtke, Aleksandra [1 ]
机构
[1] Nicolaus Copernicus Univ Torun, Fac Chem, Gagarina St 7, PL-87100 Torun, Poland
[2] Nicolaus Copernicus Univ Torun, Fac Biol & Vet Sci, Lwowska St 1, PL-87100 Torun, Poland
关键词
iron; iron-based materials; porosity; biodegradable metals; corrosion; cytotoxic activity; PURE IRON; PULMONARY-ARTERY; DEGRADATION; STENTS; CELLS; CYTOTOXICITY; BIOMATERIAL; IMMERSION; METALS;
D O I
10.3390/jfb14060293
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Biodegradable metal systems are the future of modern implantology. This publication describes the preparation of porous iron-based materials using a simple, affordable replica method on a polymeric template. We obtained two iron-based materials with different pore sizes for potential application in cardiac surgery implants. The materials were compared in terms of their corrosion rate (using immersion and electrochemical methods) and their cytotoxic activity (indirect test on three cell lines: mouse L929 fibroblasts, human aortic smooth muscle cells (HAMSC), and human umbilical vein endothelial cells (HUVEC)). Our research proved that the material being too porous might have a toxic effect on cell lines due to rapid corrosion.
引用
收藏
页数:18
相关论文
共 50 条
[31]   Rapid Casting of Biodegradable Porous Magnesium Scaffolds and Electrophoretic Deposition of 45S5 Bioactive Glass Nanoparticles Coatings on Porous Scaffolds: Characterization and In Vitro Bioactivity Analysis [J].
Temiz, Abdurrahim ;
Yaser, Mustafa ;
Alshemary, Ammar Z. ;
Akar, Neset .
INTERNATIONAL JOURNAL OF METALCASTING, 2023, 17 (03) :1871-1882
[32]   Assessment of pH Value and Release of Calcium Ions in Calcium Silicate Cements: An In Vitro Comparative Study [J].
Herrera-Trinidad, Ruben ;
Molinero-Mourelle, Pedro ;
Fonseca, Manrique ;
Weber, Adrian Roman ;
Vera, Vicente ;
Mena, Maria Luz ;
Vera-Gonzalez, Vicente .
MATERIALS, 2023, 16 (18)
[33]   Comparative Analysis of Cytotoxic Activity of New Nitrosyl Iron-Sulfur Complexes in Human Tumor Cells In Vitro [J].
Zhukova, O. S. ;
Kiselevskii, M., V ;
Fetisova, L., V ;
Borisova, L. M. ;
Malakhova, N., V ;
Kiseleva, M. P. .
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2020, 169 (01) :130-136
[34]   Comparative life cycle assessment of sewer corrosion control by iron salts: Suitability analysis and strategy optimization [J].
Wang, Xiuheng ;
Li, Lanqing ;
Bai, Shunwen ;
Yuan, Zhiguo ;
Miao, Jingyu ;
Wang, Mengyue ;
Ren, Nanqi .
WATER RESEARCH, 2021, 201
[35]   Chitosan Interaction with Iron from Yoghurt Using an In Vitro Digestive Model: Comparative Study with Plant Dietary Fibers [J].
Dello Staffolo, Marina ;
Martino, Miriam ;
Bevilacqua, Alicia ;
Montero, Mirta ;
Susana Rodriguez, Maria ;
Albertengo, Liliana .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2011, 12 (07) :4647-4660
[36]   Novel Bio-functional Magnesium Coating on Porous Ti6Al4V Orthopaedic Implants: In vitro and In vivo Study [J].
Li, Xiaokang ;
Gao, Peng ;
Wan, Peng ;
Pei, Yifeng ;
Shi, Lei ;
Fan, Bo ;
Shen, Chao ;
Xiao, Xin ;
Yang, Ke ;
Guo, Zheng .
SCIENTIFIC REPORTS, 2017, 7
[37]   HPLC Analysis of Phenolic Acids, Antioxidant Activity and in vitro Effectiveness of Green and Roasted Caffea arabica Bean Extracts: A Comparative Study [J].
El-Nabi, Sobhy Hassab ;
Dawoud, Gouda T. M. ;
El-Garawani, Islam ;
El-Shafey, Samraa .
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 18 (09) :1281-1288
[38]   Comparative Study of Spheroids (3D) and Monolayer Cultures (2D) for the In Vitro Assessment of Cytotoxicity Induced by the Mycotoxins Sterigmatocystin, Ochratoxin A and Patulin [J].
Zingales, Veronica ;
Esposito, Maria Rosaria ;
Quagliata, Martina ;
Cimetta, Elisa ;
Ruiz, Maria-Jose .
FOODS, 2024, 13 (04)
[39]   Comparative study of iron ore characterisation using a scanning electron microscope and optical image analysis [J].
Donskoi, E. ;
Manuel, J. ;
Austin, P. ;
Poliakov, A. ;
Peterson, M. ;
Hapugoda, S. .
TRANSACTIONS OF THE INSTITUTIONS OF MINING AND METALLURGY SECTION B-APPLIED EARTH SCIENCE, 2013, 122 (04) :217-229
[40]   A Comparative Study of Quercetin-Loaded Nanocochleates and Liposomes: Formulation, Characterization, Assessment of Degradation and In Vitro Anticancer Potential [J].
Munot, Neha ;
Kandekar, Ujjwala ;
Giram, Prabhanjan S. ;
Khot, Kavita ;
Patil, Abhinandan ;
Cavalu, Simona .
PHARMACEUTICS, 2022, 14 (08)