Hemorrhagic adenovirus cystitis in a newborn

被引:0
作者
Alexandre, Susana M. D. [1 ]
Matos, Carolina O. C. C. [2 ]
Fortunato, Fabiana C. F. [3 ]
Sandes, Ana R. M. C. [2 ]
机构
[1] Ctr Hosp Oeste, Serv Pediat, Rua Diario Noticias, P-2500176 Caldas Da Rainha, Portugal
[2] Ctr Hosp Univ Lisboa Norte, Hosp Santa Maria, Dept Pediat, Unidade Nefrol & Transplantacao Renal Pediat, Lisbon, Portugal
[3] Ctr Hosp Oeste, Serv Pediat, Caldas Da Rainha, Portugal
关键词
adenovirus; cystitis; hematuria; nephrology; newborn; INFECTION; HEMATURIA;
D O I
10.1515/crpm-2022-0018
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives: Gross hematuria is rare in the neonate and requires prompt etiology evaluation and intervention. This article aims to draw attention to adenovirus as a cause of hematuria in newborns. Case presentation: We present the case of a newborn admitted to the neonatal unit after birth with respiratory distress. Empiric treatment with ampicillin and gentamicin was initiated. He presented a favorable clinical and laboratory course with decreasing inflammatory parameters. On day 7 gross hematuria was detected and the urinalysis revealed red blood cells, trace of proteins and leukocytes. Cefotaxime was added after urine and blood cultures. Doppler ultrasound showed bladder sediment with no signs of renal venous thrombosis and the cultures were negative. There was a progressive improvement of gross hematuria with resolution on day 16. Urine adenovirus PCR was positive and the diagnosis of adenovirus hemorrhagic cystitis was made. Conclusions: Adenovirus should be considered as a potential etiology if clinical symptoms and urinalysis are suggestive of infection, but the urine culture is negative and ensuring that all other possible causes of hematuria are ruled of. As far as the authors know, this is the first case report of a newborn with adenovirus hemorrhagic cystitis.
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