A Reagentless Electrochemical DNA Sensor Based on a Self-Powered DNA Machine

被引：1
|
作者：
Huang, Ting [1 ,2 ]
Zhang, Wenxing [1 ,2 ]
Wie, Guobing [1 ,2 ]
Hong, Nian [1 ,2 ]
Wang, Mei [1 ,2 ]
Fan, Qiqi [1 ,2 ]
Yu, Qiangqiang [1 ,2 ]
Liao, Fusheng [1 ,2 ]
Fan, Hao [1 ,2 ]
机构：
[1] JiangXi Univ Chinese Med, Dept Pharm, Nanchang 330004, Jiangxi, Peoples R China
[2] JiangXi Univ Chinese Med, Affiliated Hosp, Nanchang 330004, Jiangxi, Peoples R China
来源：
ELECTROANALYSIS | 2023年 / 35卷 / 04期
基金：
美国国家科学基金会;
关键词：
Electrochemical DNA sensor; MOFs; Bisferrocene; Self-powered; Reagentless; SURVIVIN MESSENGER-RNA; BIOSENSOR; FRAMEWORK; FEATURES; WALKER;
D O I：
10.1002/elan.202200330
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Herein, a reagentless electrochemical DNA sensor based on a self-powered DNA machine for detecting survivin mRNA in cells is developed. The metal-organic framework (MOFs) loaded with DNAzyme cofactors (Mn2+) is coated on PTFE rods on the Au surface and assembled with the DNA walker, overcoming the complexity of adding metal ions from the external environment. In addition, the orbital chain is modified by a synthetic bisferrocene signal marker, which further enables signal amplification. Under optimal conditions, the sensor exhibits a range from 1x10(-14) mol/L to 1x10(-8) mol/L with a detection limit (S/N=3) of 1.28 fM.
引用
收藏
页数：9
相关论文
共 50 条
  • [21] Self-Powered Landslide Displacement Sensor Based on Triboelectric Nanogenerator
    Zhang, Yongquan
    Chuan, Wu
    IEEE SENSORS JOURNAL, 2023, 23 (16) : 18042 - 18049
  • [22] A Self-Powered Basketball Training Sensor Based on Triboelectric Nanogenerator
    Zhao, Zhenyu
    Wu, Chuan
    Zhou, Qing
    APPLIED SCIENCES-BASEL, 2021, 11 (08):
  • [23] Self-Powered Speed Sensor for Turbodrills Based on Triboelectric Nanogenerator
    Wu, Chuan
    Fan, Chenxing
    Wen, Guojun
    SENSORS, 2019, 19 (22)
  • [24] Stretchable Self-Powered Fiber-Based Strain Sensor
    Zhong, Junwen
    Zhong, Qize
    Hu, Qiyi
    Wu, Nan
    Li, Wenbo
    Wang, Bo
    Hu, Bin
    Zhou, Jun
    ADVANCED FUNCTIONAL MATERIALS, 2015, 25 (12) : 1798 - 1803
  • [25] Sensing performance of a self-powered electrochemical sensor for H2O2 detection based on microbial fuel cell
    Liu, Weifeng
    Yin, Lin
    Jin, Qi
    Zhu, Yimin
    Zhao, Jiao
    Zheng, Libiao
    Zhou, Zihao
    Zhu, Bin
    JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2019, 832 : 97 - 104
  • [26] A self-powered electrochemical aptasensor for the detection of 17β-estradiol based on carbon nanocages/gold nanoparticles and DNA bioconjugate mediated biofuel cells
    Wu, Yongju
    Luo, Dan
    Yi, Jinfei
    Li, Rong
    Yang, Dan
    Pang, Pengfei
    Wang, Hongbin
    Yang, Wenrong
    Zhang, Yanli
    ANALYST, 2024, 149 (09) : 2621 - 2628
  • [27] A Programmed, Autonomous, and Self-powered DNA Motor for One-Step Amplification Detection of Ochratoxin A
    Xiong, Zhengwei
    Ren, Yanrong
    Wang, Cun
    Wu, Ge
    Yun, Wen
    Chen, Hong
    Yang, Lizhu
    FOOD ANALYTICAL METHODS, 2022, 15 (04) : 847 - 855
  • [28] An effective DNA-based electrochemical switch for reagentless detection of living cells
    Liu, Jing
    Zhou, Hong
    Xu, Jing-Juan
    Chen, Hong-Yuan
    CHEMICAL COMMUNICATIONS, 2011, 47 (15) : 4388 - 4390
  • [29] Self-powered elementary hybrid magnetoelectric sensor
    Gerhardt, Martha
    Zimoch, Lukas
    Dorn, Christian
    Elzenheimer, Eric
    Bald, Christin
    Lerg, Tjorben
    Hoffmann, Johannes
    Kaps, Soeren
    Hoeft, Michael
    Schmidt, Gerhard
    Wulfinghoff, Stephan
    Adelung, Rainer
    NANO ENERGY, 2023, 115
  • [30] Design of a Self-powered Current Measuring Sensor
    Xu, Changfu
    Zhang, Shuo
    Tao, Fengbo
    Hu, Chengbo
    Xu, Jiayuan
    Zhou, Xin
    Hong, Yu
    PROCEEDINGS OF THE 2ND INTERNATIONAL CONFERENCE ON COMPUTER ENGINEERING, INFORMATION SCIENCE & APPLICATION TECHNOLOGY (ICCIA 2017), 2017, 74 : 90 - 94
12345