A Reagentless Electrochemical DNA Sensor Based on a Self-Powered DNA Machine

被引：1
|
作者：
Huang, Ting [1 ,2 ]
Zhang, Wenxing [1 ,2 ]
Wie, Guobing [1 ,2 ]
Hong, Nian [1 ,2 ]
Wang, Mei [1 ,2 ]
Fan, Qiqi [1 ,2 ]
Yu, Qiangqiang [1 ,2 ]
Liao, Fusheng [1 ,2 ]
Fan, Hao [1 ,2 ]
机构：
[1] JiangXi Univ Chinese Med, Dept Pharm, Nanchang 330004, Jiangxi, Peoples R China
[2] JiangXi Univ Chinese Med, Affiliated Hosp, Nanchang 330004, Jiangxi, Peoples R China
来源：
ELECTROANALYSIS | 2023年 / 35卷 / 04期
基金：
美国国家科学基金会;
关键词：
Electrochemical DNA sensor; MOFs; Bisferrocene; Self-powered; Reagentless; SURVIVIN MESSENGER-RNA; BIOSENSOR; FRAMEWORK; FEATURES; WALKER;
D O I：
10.1002/elan.202200330
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Herein, a reagentless electrochemical DNA sensor based on a self-powered DNA machine for detecting survivin mRNA in cells is developed. The metal-organic framework (MOFs) loaded with DNAzyme cofactors (Mn2+) is coated on PTFE rods on the Au surface and assembled with the DNA walker, overcoming the complexity of adding metal ions from the external environment. In addition, the orbital chain is modified by a synthetic bisferrocene signal marker, which further enables signal amplification. Under optimal conditions, the sensor exhibits a range from 1x10(-14) mol/L to 1x10(-8) mol/L with a detection limit (S/N=3) of 1.28 fM.
引用
收藏
页数：9
相关论文
共 50 条
  • [11] Electrochemical self-powered strain sensor for static and dynamic strain detections
    Huang, Qi
    Jiang, Yadong
    Duan, Zaihua
    Wu, Yuanming
    Yuan, Zhen
    Zhang, Mingxiang
    Zhao, Qiuni
    Zhang, Yajie
    Liu, Bohao
    Tai, Huiling
    NANO ENERGY, 2023, 118
  • [12] Self-powered wearable electrochemical sensor based on composite conductive hydrogel medium for detection of lactate in human sweat
    Sun, Jing
    Dai, Wanqing
    Guo, Qiang
    Gao, Yaru
    Chen, Jiayu
    Chen, Jian Lin
    Mao, Guozhu
    Sun, Hongyan
    Peng, Yung-Kang
    BIOSENSORS & BIOELECTRONICS, 2025, 277
  • [13] Self-Powered Magnetic Sensor Based on a Triboelectric Nanogenerator
    Yang, Ya
    Lin, Long
    Zhang, Yue
    Jing, Qingshen
    Hou, Te-Chien
    Wang, Zhong Lin
    ACS NANO, 2012, 6 (11) : 10378 - 10383
  • [14] Triboelectric Nanogenerator Based Self-Powered Tilt Sensor
    Iqbal, Faisal
    Shafi, Muhammad
    Khattak, Muhammad Irfan
    Nawaz, Aamir
    TEHNICKI VJESNIK-TECHNICAL GAZETTE, 2018, 25 (02): : 325 - 328
  • [15] Study on the Self-powered electromagnetic sensor
    Zhang Ruilan
    Jin Wenhe
    Zhou Jun
    Li Shuguang
    INDUSTRIAL DESIGN AND MECHANICS POWER II, 2013, 437 : 650 - +
  • [16] Electrochemical humidity sensor enabled self-powered wireless humidity detection system
    Zhang, Mingxiang
    Duan, Zaihua
    Zhang, Boyu
    Yuan, Zhen
    Zhao, Qiuni
    Jiang, Yadong
    Tai, Huiling
    NANO ENERGY, 2023, 115
  • [17] Advanced triboelectric nanogenerator based self-powered electrochemical system
    Xuan, Ningning
    Song, Chunhui
    Cheng, Gang
    Du, Zuliang
    CHEMICAL ENGINEERING JOURNAL, 2024, 481
  • [18] Self-powered Pressure Sensor Based on Flexible Magnetic Material
    Guo, Chengxi
    Kong, Lijie
    Chen, Yian
    Jiang, Yuan
    Zhang, Qinyan
    Qian, Xilin
    Li, Yifeng
    Huang, Jianqiu
    Yu, Huiyang
    2023 IEEE SENSORS, 2023,
  • [19] A self-powered AC magnetic sensor based on piezoelectric nanogenerator
    Yu, Aifang
    Song, Ming
    Zhang, Yan
    Kou, Jinzong
    Zhai, Junyi
    Wang, Zhong Lin
    NANOTECHNOLOGY, 2014, 25 (45)
  • [20] A New Self-Powered Temperature Sensor Based on Thermoelectric Generators
    Hassanzadeh, Alireza
    Baghestani, Sajjad
    IEEE SENSORS JOURNAL, 2022, 22 (23) : 22421 - 22427
12345