Diabetic Kidney Disease in Post-Kidney Transplant Patients

被引：1
作者：
Pham, Ngoc-Yen T. [1 ]
Cruz, Diego [2 ]
Madera-Marin, Luis [1 ]
Ravender, Raja [1 ]
Garcia, Pablo [1 ]
机构：
[1] Univ New Mexico, Sch Med, Div Nephrol, Albuquerque, NM 87106 USA
[2] Hosp Gen San Juan Dios, Guatemala City 01001, Guatemala
来源：
JOURNAL OF CLINICAL MEDICINE | 2024年 / 13卷 / 03期
关键词：
PTDM; kidney transplant; diabetic nephropathy; diabetes; BASAL INSULIN THERAPY; LONG-TERM; RENAL-TRANSPLANTATION; IMMUNOSUPPRESSIVE DRUGS; CARDIOVASCULAR OUTCOMES; GLUCOSE-METABOLISM; RAPAMYCIN TOXICITY; MTOR INHIBITION; UNITED-STATES; DOUBLE-BLIND;
D O I：
10.3390/jcm13030793
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Post-transplant diabetes mellitus (PTDM) is a common occurrence in post-kidney transplantation and is associated with greater mortality, allograft failure, and increased risk of infections. The primary goal in the management of PTDM is to achieve glycemic control to minimize the risk of complications while balancing the need for immunosuppression to maintain the health of the transplanted kidney. This review summarizes the effects of maintenance immunosuppression and therapeutic options among kidney transplant recipients. Patients with PTDM are at increased risk of diabetic kidney disease development; therefore, in this review, we focus on evidence supporting the use of novel antidiabetic agents and discuss their benefits and potential side effects in detail.
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页数：18
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