Diabetic Kidney Disease in Post-Kidney Transplant Patients

被引：3

作者：

Pham, Ngoc-Yen T. ^{[1
]}

Cruz, Diego ^{[2
]}

Madera-Marin, Luis ^{[1
]}

Ravender, Raja ^{[1
]}

Garcia, Pablo ^{[1
]}

机构：

[1] Univ New Mexico, Sch Med, Div Nephrol, Albuquerque, NM 87106 USA

[2] Hosp Gen San Juan Dios, Guatemala City 01001, Guatemala

来源：

JOURNAL OF CLINICAL MEDICINE | 2024年 / 13卷 / 03期

关键词：

PTDM; kidney transplant; diabetic nephropathy; diabetes; BASAL INSULIN THERAPY; LONG-TERM; RENAL-TRANSPLANTATION; IMMUNOSUPPRESSIVE DRUGS; CARDIOVASCULAR OUTCOMES; GLUCOSE-METABOLISM; RAPAMYCIN TOXICITY; MTOR INHIBITION; UNITED-STATES; DOUBLE-BLIND;

D O I：

10.3390/jcm13030793

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Post-transplant diabetes mellitus (PTDM) is a common occurrence in post-kidney transplantation and is associated with greater mortality, allograft failure, and increased risk of infections. The primary goal in the management of PTDM is to achieve glycemic control to minimize the risk of complications while balancing the need for immunosuppression to maintain the health of the transplanted kidney. This review summarizes the effects of maintenance immunosuppression and therapeutic options among kidney transplant recipients. Patients with PTDM are at increased risk of diabetic kidney disease development; therefore, in this review, we focus on evidence supporting the use of novel antidiabetic agents and discuss their benefits and potential side effects in detail.

引用

页数：18

共 110 条

[1] Efficacy and Safety of Dipeptidyl Peptidase-4 Inhibitors in Kidney Transplant Recipients with Post-transplant Diabetes Mellitus (PTDM)-a Systematic Review and Meta-Analysis [J].

Abdelaziz, Tarek Samy ;

Ali, Ahmed Yamany ;

Fatthy, Moataz .

CURRENT DIABETES REVIEWS, 2020, 16 (06) :580-585

[2] Infectious complications after kidney transplantation: current epidemiology and associated risk factors [J].

Alangaden, George J. ;

Thyagarajan, Rama ;

Gruber, Scott A. ;

Morawski, Katherina ;

Garnick, James ;

El-Amm, Jose M. ;

West, Miguel S. ;

Sillix, Dale H. ;

Chandrasekar, Pranatharthi H. ;

Haririan, Abdolreza .

CLINICAL TRANSPLANTATION, 2006, 20 (04) :401-409

[3] Outcomes of SGLT2 Inhibitors Use in Diabetic Renal Transplant Patients [J].

AlKindi, Fatima ;

Al-Omary, Hanan L. ;

Hussain, Qutaiba ;

Al Hakim, Mohamed ;

Chaaban, Ahmed ;

Boobes, Yousef .

TRANSPLANTATION PROCEEDINGS, 2020, 52 (01) :175-178

[4]

Allison AC, 1996, CLIN TRANSPLANT, V10, P77

[5] Transplantation and diabetes (Transdiab): a pilot randomised controlled trial of metformin in impaired glucose tolerance after kidney transplantation [J].

Alnasrallah, Basil ;

Goh, Tze Liang ;

Chan, Lai Wan ;

Manley, Paul ;

Pilmore, Helen .

BMC NEPHROLOGY, 2019, 20 (1)

[6] mTORC1 Signaling: A Double-Edged Sword in Diabetic β Cells [J].

Ardestani, Amin ;

Lupse, Blaz ;

Kido, Yoshiaki ;

Leibowitz, Gil ;

Maedler, Kathrin .

CELL METABOLISM, 2018, 27 (02) :314-331

[7] Roles of mTOR in the Regulation of Pancreatic β-Cell Mass and Insulin Secretion [J].

Asahara, Shun-ichiro ;

Inoue, Hiroyuki ;

Watanabe, Hitoshi ;

Kido, Yoshiaki .

BIOMOLECULES, 2022, 12 (05)

[8] Use of Empagliflozin in Recipients of Kidney Transplant: A Report of 8 Cases [J].

Attallah, Nizar ;

Yassine, Lina .

TRANSPLANTATION PROCEEDINGS, 2019, 51 (10) :3275-3280

[9] Effects of Dipeptidyl Peptidase-4 Inhibitors on Hyperglycemia and Blood Cyclosporine Levels in Renal Transplant Patients with Diabetes: A Pilot Study [J].

Bae, Jaehyun ;

Lee, Min Jung ;

Choe, Eun Yeong ;

Jung, Chang Hee ;

Wang, Hye Jin ;

Kim, Myoung Soo ;

Kim, Yu Seun ;

Park, Joong-Yeol ;

Kang, Eun Seok .

ENDOCRINOLOGY AND METABOLISM, 2016, 31 (01) :161-167

[10] Rosiglitazone treatment of diabetes mellitus after solid organ transplantation [J].

Baldwin, D ;

Duffin, KE .

TRANSPLANTATION, 2004, 77 (07) :1009-1014

← 1 2 3 4 5 6 7 8 9 10 →