Association between short-term exposure to ambient air pollution and number of outpatient Helicobacter pylori infection visits

被引:4
作者
Ma, Lizuo [1 ]
Lin, Zhijing [2 ,3 ]
Wang, Jiaoxue [4 ]
Ye, Ruirui [5 ]
Li, Yuefang [6 ]
Chen, Ping [2 ,3 ]
Yuan, Zhi [2 ,3 ]
Yang, Liyan [2 ,3 ]
Miao, Lin [2 ,3 ]
Li, Jiehua [1 ]
机构
[1] Anhui Med Univ, Dept Geriatr, Affiliated Hosp 1, 218 Jixi Rd, Hefei 230022, Anhui, Peoples R China
[2] Anhui Med Univ, Sch Publ Hlth, Dept Toxicol, Hefei 230032, Peoples R China
[3] Anhui Med Univ, Key Lab Environm Toxicol, Anhui Higher Educ Inst, Hefei 230032, Peoples R China
[4] 901st Hosp Joint Logist Support Force Chinese Peo, Dept Gastroenterol, Hefei 230032, Anhui, Peoples R China
[5] Anhui Med Univ, Dept Gen Practice, Affiliated Hosp 1, Hefei 230032, Peoples R China
[6] 901st Hosp Joint Logist Support Force Chinese Peo, Dept Geriatr, Hefei 230032, Peoples R China
关键词
Air pollution; Helicobacter pylori infection; Outpatient visit; Case-crossover design; Exposure-response relationship; PARTICULATE MATTER; ULCER DISEASE; ADMISSIONS; MORTALITY;
D O I
10.1007/s11356-022-23826-8
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Helicobacter pylori infection (HPI) is an important risk factor of gastrointestinal diseases, but factors leading to it are still not fully understood. To investigate the association between short-term exposure to air pollution and HPI during outpatient visits, we collected daily data for HPI outpatient visits and air pollutant concentrations during 2014-2021 in Hefei, Anhui Province, China. A time-stratified case-crossover design was performed to analyze the acute impacts of air pollution on HPI outpatient visits. We also explored potential effect modifiers. A total of 9072 outpatient visits were recorded. We found positive and statistically significant associations of acute exposure to nitrogen dioxide (NO2), sulfur dioxide (SO2), and carbon monoxide (CO) with HPI outpatient visits. Threshold concentrations of the three pollutants with same-day exposure (lag 0 day) for outpatient visits were 37 mu g/m(3) for NO2, 8 mu g/m(3) for SO2, and 0.8 mg/m(3) for CO. The odds ratios for HPI outpatient visits at the 95th percentile of NO2, SO2, and CO against the thresholds were 1.207 (1.120-1.302), 1.175 (1.052-1.312), and 1.110 (1.019-1.209), respectively. The associations were more evident in patients older than 45 years, females, with health insurance, and in cold seasons. Null associations of exposure to either ozone (O-3) or particulate matter (PM) were observed. In summary, short-term exposure to NO2, SO2, and CO above certain concentrations, but not PM or O-3, may trigger the increased risk of outpatient visits due to HP infection in Chinese population.
引用
收藏
页码:22808 / 22815
页数:8
相关论文
共 28 条
[1]   Exposure to traffic-related air pollution and the composition of the gut microbiota in overweight and obese adolescents [J].
Alderete, Tanya L. ;
Jones, Roshonda B. ;
Chen, Zhanghua ;
Kim, Jeniffer S. ;
Habre, Rima ;
Lurmann, Frederick ;
Gilliland, Frank D. ;
Goran, Michael I. .
ENVIRONMENTAL RESEARCH, 2018, 161 :472-478
[2]  
Bigard MA, 1996, GASTROEN CLIN BIOL, V20, pS1
[3]   Ambient air pollution and daily hospital admissions for mental disorders in Shanghai, China [J].
Chen, Chen ;
Liu, Cong ;
Chen, Renjie ;
Wang, Weibing ;
Li, Weihua ;
Kan, Haidong ;
Fu, Chaowei .
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 613 :324-330
[4]   The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in children [J].
Chen Li'e ;
Che Juan ;
Jiang Dongying ;
Feng Guiling ;
Zheng Tihua ;
Wang Yanfei .
SAO PAULO MEDICAL JOURNAL, 2017, 135 (01) :29-33
[5]   Helicobacter pylori Infection in Croatian Population: Knowledge, Attitudes and Factors Influencing Incidence and Recovery [J].
Cindro, Pavle Vrebalov ;
Bukic, Josipa ;
Leskur, Dario ;
Rusic, Doris ;
Perisin, Ana Seselja ;
Bozic, Josko ;
Vukovic, Jonatan ;
Modun, Darko .
HEALTHCARE, 2022, 10 (05)
[6]   Exploring the interactions between Helicobacter pylori (Hp) infection and other risk factors of gastric cancer: A pooled analysis in the Stomach cancer Pooling (StoP) Project [J].
Collatuzzo, Giulia ;
Pelucchi, Claudio ;
Negri, Eva ;
Lopez-Carrillo, Lizbeth ;
Tsugane, Shoichiro ;
Hidaka, Akihisa ;
Hamada, Gerson Shigueaki ;
Hernandez-Ramirez, Raul Ulises ;
Lopez-Cervantes, Malaquias ;
Malekzadeh, Reza ;
Pourfarzi, Farhad ;
Mu, Lina ;
Zhang, Zuo-Feng ;
Lunet, Nuno ;
La Vecchia, Carlo ;
Boffetta, Paolo .
INTERNATIONAL JOURNAL OF CANCER, 2021, 149 (06) :1228-1238
[7]   Air Pollution and Mortality in the Medicare Population [J].
Di, Qian ;
Wang, Yan ;
Zanobetti, Antonella ;
Wang, Yun ;
Koutrakis, Petros ;
Choirat, Christine ;
Dominici, Francesca ;
Schwartz, Joel D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (26) :2513-2522
[8]   Ambient air pollution and cause-specific risk of hospital admission in China: A nationwide time-series study [J].
Gu, Jiangshao ;
Shi, Ying ;
Zhu, Yifang ;
Chen, Ning ;
Wang, Haibo ;
Zhang, Zongjiu ;
Chen, Ting .
PLOS MEDICINE, 2020, 17 (08)
[9]   Long-term exposure to ambient fine particles and gastrointestinal cancer mortality in Taiwan: A cohort study [J].
Guo, Cui ;
Chan, Ta-Chien ;
Teng, Yung-Chu ;
Lin, Changqing ;
Bo, Yacong ;
Chang, Ly-Yun ;
Lau, Alexis K. H. ;
Tam, Tony ;
Wong, Martin C. S. ;
Lao, Xiang Qian .
ENVIRONMENT INTERNATIONAL, 2020, 138
[10]   Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis [J].
Hooi, James K. Y. ;
Lai, Wan Ying ;
Ng, Wee Khoon ;
Suen, Michael M. Y. ;
Underwood, Fox E. ;
Tanyingoh, Divine ;
Malfertheiner, Peter ;
Graham, David Y. ;
Wong, Vincent W. S. ;
Wu, Justin C. Y. ;
Chan, Francis K. L. ;
Sung, Joseph J. Y. ;
Kaplan, Gilaad G. ;
Ng, Siew C. .
GASTROENTEROLOGY, 2017, 153 (02) :420-429