Assessment of pulmonary artery size at birth as a prognostic factor in congenital diaphragmatic hernia: results of a multicenter study in Japan

被引:0
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作者
Okazaki, Tadaharu [1 ]
Terui, Keita [2 ]
Nagata, Kouji [3 ]
Hayakawa, Masahiro [4 ]
Okuyama, Hiroomi [5 ]
Amari, Shoichiro [6 ]
Masumoto, Kouji [7 ]
Yamoto, Masaya [8 ]
Inamura, Noboru [9 ]
Toyoshima, Katsuaki [10 ]
Furukawa, Taizo [11 ]
Okawada, Manabu [12 ]
Yokoi, Akiko [13 ]
Koike, Yuki [14 ]
Nojiri, Shuko [15 ]
Nishizaki, Yuji [16 ]
Yanagisawa, Naotake [15 ]
Usui, Noriaki [17 ]
机构
[1] Juntendo Univ, Dept Pediat Surg, Urayasu Hosp, Chiba, Japan
[2] Chiba Univ, Grad Sch Med, Dept Pediat Surg, Chiba, Japan
[3] Kyushu Univ, Dept Pediat Surg, Fukuoka, Japan
[4] Nagoya Univ Hosp, Ctr Maternal Neonatal Care, Nagoya, Japan
[5] Osaka Univ, Dept Pediat Surg, Grad Sch Med, Osaka, Japan
[6] Natl Ctr Child Hlth & Dev, Div Neonatol, Tokyo, Japan
[7] Univ Tsukuba, Fac Med, Dept Pediat Surg, Tsukuba, Japan
[8] Shizuoka Childrens Hosp, Dept Pediat Surg, Shizuoka, Japan
[9] Kindai Univ, Fac Med, Dept Pediat, Osaka, Japan
[10] Kanagawa Childrens Med Ctr, Dept Neonatol, Yokohama, Japan
[11] Kyoto Prefectural Univ Med, Dept Pediat Surg, Kyoto, Japan
[12] Juntendo Univ, Dept Pediat Gen & Urogenital Surg, Sch Med, Tokyo, Japan
[13] Hyogo Childrens Hosp, Dept Pediat Surg, Hyogo, Japan
[14] Mie Univ, Dept Pediat Surg, Tsu, Mie, Japan
[15] Juntendo Univ, Med Technol Innovat Ctr, Clin Res & Trial Ctr, Tokyo, Japan
[16] Juntendo Univ, Div Medial Educ, Sch Med, Tokyo, Japan
[17] Osaka Womens & Childrens Hosp, Dept Pediat Surg, Izumi, Japan
关键词
ECHOCARDIOGRAPHIC PREDICTORS; LUNG HYPOPLASIA; INFANTS; MORTALITY; DIAMETERS; MCGOON;
D O I
10.1038/s41372-023-01750-0
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
ObjectiveTo assess the reliability of pulmonary artery (PA) parameters as a prognostic marker in neonates with isolated left-sided congenital diaphragmatic hernia (IL-CDH).Study designA retrospective cohort study conducted by the Japanese CDH Study Group (JCDHSG).Results323 IL-CDH patients registered with the JCDHSG were included. 272 patients survived to 90 days of age. Right PA (RPA) and left PA (LPA) diameters and pulmonary artery index (PAIndex) at birth were significantly larger in survivors. The cutoff values of RPA and LPA diameters and PAIndex for survival up to 90 days were 3.2 mm, 2.8 mm and 83.7, respectively, and logistic regression analysis showed that these were significantly related to survival. Multiple logistic regression analysis showed that both the PA parameters and liver herniation were significantly related to survival.ConclusionsThe three PA parameters at birth can predict clinical outcomes and are considered as independent risk factors of liver herniation.
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收藏
页码:1295 / 1300
页数:6
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