Risk factors for uncontrolled blood pressure among individuals with hypertension on treatment: the CONSTANCES population-based study

被引:4
作者
Cherfane, Michelle [1 ,2 ,3 ]
Vallee, Alexandre [4 ,5 ]
Kab, Sofiane [6 ]
Salameh, Pascale [1 ,3 ,7 ,8 ]
Goldberg, Marcel [4 ,6 ]
Zins, Marie [4 ,6 ,9 ]
Blacher, Jacques [2 ,5 ]
机构
[1] Lebanese Amer Univ, Gilbert & Rose Marie Chagoury Sch Med, Populat Hlth Div, Byblos, Lebanon
[2] Paris 13 Univ, Nutr Epidemiol Res Unit EREN, Inserm, Sorbonne Paris Cite,U1153, Bobigny, France
[3] Inst Natl St Publ Epidemiol Clin & Toxicol Liban I, INSPECT LB, Beirut, Lebanon
[4] Univ Paris Cite, Fac Med, Paris, France
[5] Hop Hotel Dieu, AP HP, Hypertens & Cardiovasc Prevent Unit, Diag & Therapeut Ctr, Paris, France
[6] Inserm, UMS011, Populat Based Epidemiol Cohorts Unit, Villejuif, France
[7] Univ Nicosia, Med Sch, Dept Primary Care & Populat Hlth, Nicosia, Cyprus
[8] Lebanese Univ, Fac Pharm, Hadath, Lebanon
[9] Hop Hotel Dieu, Diag & Therapeut Ctr, Hypertens & Cardiovasc Prevent Unit, 1 Parvis Notre Dame,Pl Jean Paul 2, F-75004 Paris, France
关键词
Epidemiology; risk factors; uncontrolled hypertension; lifestyle behaviour; socio-economic status; AGE-RELATED-CHANGES; MANAGEMENT; AWARENESS; PREVALENCE; PREDICTORS; PATTERNS; PROGRAM; ADULTS; HEALTH; INCOME;
D O I
10.1093/ije/dyae027
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background We aimed to assess factors associated with uncontrolled blood pressure (BP) among individuals with hypertension on treatment, by sex.Methods We conducted a nested cross-sectional analysis using data from the population-based cohort study CONSTANCES, designed as a randomly selected sample of French adults aged 18-69 years at study inception. We included 11 760 participants previously diagnosed with hypertension and taking antihypertensive medications. Uncontrolled BP was defined as mean systolic BP >= 140 mmHg and/or mean diastolic BP >= 90 mmHg. Sex-specific age-adjusted multivariable analyses were performed using logistic regression models stratified by stages of uncontrolled hypertension.Results The mean age of participants was 59.4 years. The prevalence of uncontrolled BP was 51.4%, and it was higher in men than in women [adjusted odds ratio (aOR), 1.80; 95% CI, 1.67-1.94]. In both sexes, the lower the age, the lower the prevalence of uncontrolled hypertension. Low level of education and history of cardiovascular events had, respectively, higher and lower odds of uncontrolled BP. In men, additional risk factors included overweight and obesity (aOR, 1.15; 95% CI, 1.00-1.32; and aOR, 1.45; 95% CI, 1.23-1.70, respectively), lack of physical activity (aOR, 1.20; 95% CI, 1.04-1.40), low adherence to a Dietary Approach to Stop Hypertension diet (aOR, 1.21; 95% CI, 1.05-1.40) and heavy alcohol consumption (aOR, 1.33; 95% CI, 1.08-1.63), with the last two factors persisting across different stages of uncontrolled BP.Conclusions From a population-based perspective, socio-economic and behavioural characteristics were risk factors for uncontrolled hypertension, but they differed by sex and by stage of uncontrolled hypertension. Modifiable risk factors, such as weight, diet, physical activity and alcohol consumption, have an important role in the control of hypertension.
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页数:10
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