Association between Sleep Duration and Colorectal Adenomas: Findings from a Case-Control Study in Vietnam

被引：0

作者：

Tran, Chi Thi-Du ^{[1
,2
,3
]}

Paragomi, Pedram ^{[4
]}

Tran, Mo Thi ^{[1
]}

Nguyen, Mai Vu-Tuyet ^{[1
]}

Tuong, Thuy Thi-Van ^{[1
]}

Tran, Quang Hong ^{[1
]}

Le, Linh Cu ^{[2
]}

Pham, Huong Thi-Thu ^{[5
]}

Ha, Hien Thi-Thu ^{[6
]}

Bui, Nam Chi ^{[5
]}

Vu, Hien Huy ^{[5
]}

Ta, Phuong Que ^{[5
]}

Shrubsole, Martha J. ^{[7
,8
]}

Cai, Qiuyin ^{[7
,8
]}

Ye, Fei ^{[7
,8
]}

Le, Song Huu ^{[9
]}

Van Vu, Khien ^{[10
]}

Thi-Thanh, Huong ^{[11
,12
]}

Van Tran, Thuan ^{[11
,13
]}

Boffetta, Paolo ^{[14
,15
]}

Shu, Xiao-Ou ^{[6
]}

Luu, Hung N. ^{[4
,16
,17
]}

机构：

[1] Vinmec Healthcare Syst, Vietnam Colorectal Canc & Polyps Res Program, Hanoi, Vietnam

[2] VinUniv VinUni, Coll Hlth Sci, Hanoi, Vietnam

[3] Vinmec Healthcare Syst, Ctr Appl Sci Regenerat Med & Adv Technol, Hanoi, Vietnam

[4] Univ Pittsburgh Med Ctr UPMC, UPMC Hillman Canc Ctr, Pittsburgh, PA USA

[5] Vinmec Int Hosp Times City, Dept Gastroenterol, Vinmec Healthcare Syst, Hanoi, Vietnam

[6] Vinmec Hlth Care Syst, Vinmec Int Hosp Times city, Dept Histopathol, Hanoi, Vietnam

[7] Vanderbilt Univ, Sch Med, Vanderbilt Epidemiol Ctr, Div Epidemiol,Dept Med,Sch Med, Nashville, TN USA

[8] Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Sch Med, Nashville, TN USA

[9] Ctr Mol & Genet Res, Hanoi, Vietnam

[10] Dept Gastroenterol, Hanoi, Vietnam

[11] Vietnam Natl Canc Hosp, Vietnam Natl Canc Inst, Hanoi, Vietnam

[12] Hanoi Med Univ, Dept Eth & Med Psychol, Hanoi, Vietnam

[13] Vietnam Minist Hlth, Hanoi, Vietnam

[14] SUNY Stony Brook, Stony Brook Canc Ctr, Stony Brook, NY 11794 USA

[15] Univ Bologna, Dept Med & Surg Sci, Bologna, Italy

[16] Univ Pittsburgh, Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA

[17] Univ Pittsburgh, Div Canc Control & Populat Sci, Med Ctr, 5150 Ctr Ave, Pittsburgh, PA 15232 USA

来源：

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION | 2023年 / 32卷 / 09期

关键词：

LIFE-STYLE FACTORS; HEALTH OUTCOMES; BREAST-CANCER; RISK-FACTORS; SHIFT WORK; MELATONIN; WOMEN; POLYP; HORMONES; SMOKING;

D O I：

10.1158/1055-9965.EPI-23-0056

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Colorectal cancer is one of the leading cancers worldwide and in Vietnam. Adenomas are important precursors of colorectal cancer. Study on the association between sleep duration and development of colorectal adenoma (CRA) is limited, particularly among Vietnamese population.Methods: We conducted an individually matched case-control study of 870 CRA cases and 870 controls in a large-scale colorectal screening program involving 103,542 individuals ages & GE;40 years old in Hanoi, Vietnam. Sleep duration was categorized in three groups: short: & LE;6 hours/day, normal: 7 to 8 hours/day, and long: >8 hours/ day. Conditional logistic regression was used to evaluate the association between sleep duration and adenomas risk after controlling for potential confounders.Results: Overall, short-sleep duration was associated with increased risk of having CRA compared with normal duration [OR, 1.48; 95% confidence interval (CI), 1.12-1.97]. This pattern was present in both females (OR, 1.58; 95% CI, 1.14-2.18) and males (OR, 1.45; 95% CI, 1.08-1.93), with advanced adenomas (OR, 1.61; 95% CI, 1.09-2.38) and non-advanced adenomas (OR, 1.66; 95% CI, 1.19-2.32). Furthermore, the association between CRA development and short-sleep duration was more apparent among females who were nondrinker, nonobese, physically active, with proximal or both sided adenomas and with cardiometabolic disorder. Among males, the short-sleep duration was associated with CRA risk among never-smoking, cardiometabolic disorders, and obese.Conclusions: Short-sleep duration was associated with increased prevalence of both advanced and non-advanced CRAs among Vietnamese population.

引用

页码：1160 / 1168

页数：9