Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney

被引：9

作者：

Botelho, Ana R. ^{[1
]}

Silva, Hugo F. ^{[2
]}

Martins, Ines S. ^{[3
]}

Carneiro, Isa C. ^{[4
,5
,6
]}

Carvalho, Sonia D. ^{[4
,5
,7
]}

Henrique, Rui M. ^{[4
,5
,8
]}

V. Tuchin, Valery ^{[9
,10
,11
]}

Oliveira, Luis M. ^{[1
]}

机构：

[1] Polytech Porto Sch Engn ISEP, Phys Dept, Porto, Portugal

[2] Univ Porto, Sch Engn, Porto, Portugal

[3] ISEP, Ctr Innovat Engn & Ind Technol, Porto, Portugal

[4] Portuguese Oncol Inst Porto, Dept Pathol & Canc Biol, Porto, Portugal

[5] Portuguese Oncol Inst Porto, Epigenet Grp, Porto, Portugal

[6] Polytech Porto Sch Hlth ESS, Dept Pathol Cytolog & Thanatol Anat, Porto, Portugal

[7] St Luzia Hosp ULSAM, Dept Pathol, Viana Do Castelo, Portugal

[8] Porto Univ Inst Biomed Sci Abel Salazar, Dept Pathol & Mol Immunol, Porto, Portugal

[9] Saratov NG Chernyshevskii State Univ, Sci Med Ctr, Saratov, Russia

[10] Tomsk State Univ, Lab Laser Mol Imaging & Machine Learning, Tomsk, Russia

[11] Russian Acad Sci, Inst Precis Mech & Control, Lab Laser Diagnost Tech & Living Syst, FRC Saratov Res Ctr, Saratov, Russia

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2023年 / 286卷

关键词：

Human kidney; Chromophobe renal cell carcinoma; Spectral absorption coefficient; Melanin; Lipofuscin; Renal cancer discrimination; ABSORPTION; DISEASE;

D O I：

10.1016/j.saa.2022.122002

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

A fast calculation method was used to obtain the spectral optical properties of human normal and pathological (chromophobe renal cell carcinoma) kidney tissues. Using total transmittance, total reflectance and collimated transmittance spectra acquired from ex vivo kidney samples, the spectral optical properties of both tissues, namely the absorption, the scattering and the reduced scattering coefficients, as well as the scattering anisotropy, dispersion and light penetration depth, were calculated between 200 and 1000 nm. Analysis of the mean absorption coefficient spectra of the kidney tissues showed that both contain melanin and lipofuscin, and that 83 % of the melanin in the normal kidney converts into lipofuscin in the pathological kidney.

引用

页数：7

共 26 条

[1] Optical properties of peritoneal biological tissues in the spectral range of 350-2500 nm [J].

Bashkatov, A. N. ;

Genina, E. A. ;

Kozintseva, M. D. ;

Kochubei, V. I. ;

Gorodkov, S. Yu. ;

Tuchin, V. V. .

OPTICS AND SPECTROSCOPY, 2016, 120 (01) :1-8

[2]

Botelho A. R., 2021, THESIS POLYTECHNIC P

[3] Kinetics of Optical Properties of Colorectal Muscle During Optical Clearing [J].

Carneiro, Isa ;

Carvalho, Sonia ;

Henrique, Rui ;

Oliveira, Luis ;

Tuchin, Valery V. .

IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 2019, 25 (01)

[4] Lipofuscin-Type Pigment as a Marker of Colorectal Cancer [J].

Carvalho, Sonia ;

Carneiro, Isa ;

Henrique, Rui ;

Tuchin, Valery ;

Oliveira, Luis .

ELECTRONICS, 2020, 9 (11)

[5]

Center of Innovation in Engineering and Industrial Technology ISEP, 2022, Journal of Biomedical Photonics & Engineering, V8, DOI [10.18287/jbpe22.08.010304, DOI 10.18287/JBPE22.08.010304, 10.18287/JBPE22.08.010304]

[6] Phase measurement of light absorption and scatter in human tissue [J].

Chance, B ;

Cope, M ;

Gratton, E ;

Ramanujam, N ;

Tromberg, B .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1998, 69 (10) :3457-3481

[7] Diffuse reflectance and machine learning techniques to differentiate colorectal cancer ex vivo [J].

Fernandes, Luis ;

Carvalho, Sonia ;

Carneiro, Isa ;

Henrique, Rui ;

Tuchin, Valery V. ;

Oliveira, Helder P. ;

Oliveira, Luis M. .

CHAOS, 2021, 31 (05)

[8] Comprehensive review of chromophobe renal cell carcinoma [J].

Garje, Rohan ;

Elhag, Dean ;

Yasin, Hesham A. ;

Acharya, Luna ;

Vaena, Daniel ;

Dahmoush, Laila .

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2021, 160

[9] Determining the refractive index of human hemoglobin solutions by Kramers-Kronig relations with an improved absorption model [J].

Gienger, Jonas ;

Gross, Hermann ;

Neukammer, Joerg ;

Baer, Markus .

APPLIED OPTICS, 2016, 55 (31) :8951-8961

[10] Spectral Optical Properties of Rabbit Brain Cortex between 200 and 1000 nm [J].

Goncalves, Tania M. ;

Martins, Ines S. ;

Silva, Hugo F. ;

Tuchin, Valery V. ;

Oliveira, Luis M. .

PHOTOCHEM, 2021, 1 (02) :190-208

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