Synthesis, crystal structure and antifungal activities of new quinoline derivatives

被引：7

作者：

Sun, Xin-Peng ^{[1
,3
]}

Yu, Wei ^{[1
,3
]}

Min, Li-Jing ^{[2
]}

Han, Liang ^{[1
]}

Sun, Na-Bo ^{[3
]}

Liu, Xing-Hai ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Peoples R China

[2] Huzhou Univ, Coll Life Sci, Key Lab Vector Biol & Pathogen Control Zhejiang Pr, Huzhou 313000, Zhejiang, Peoples R China

[3] Zhejiang Shuren Univ, Coll Biol & Environm Engn, Hangzhou 310015, Zhejiang, Peoples R China

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2023年 / 1277卷

关键词：

Quinoline; Synthesis; Diphenyl ether; Antifungal activity; HERBICIDAL ACTIVITY; DESIGN;

D O I：

10.1016/j.molstruc.2022.134792

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A series of new quinoline ester derivatives containing diphenyl ether motif were designed and synthesized using 4-chlorophenol, 1-chloro-2-nitrobenzene, as raw materials via four steps. The structures were confirmed by 1 H NMR and HRMS. The compound 8-(4-chlorophenoxy)-2,3-dimethylquinolin-4-(4-chloro) benzoate (4j) exhibited moderate fungicidal activity (68.2% inhibition) against the plant pathogens Sclerotinia sclerotiorum at 50 mu g/mL.(c) 2022 Elsevier B.V. All rights reserved.

引用

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